نتایج جستجو برای: leptomeningeal metastasis

تعداد نتایج: 133009  

Journal: :International Journal of Radiation Oncology*Biology*Physics 2018

Journal: :Archives of neurology 2010
Morris D Groves

The management of patients with leptomeningeal metastases (LM) is multifaceted and complex. Even with an aggressive approach, therapeutic outcomes are uniformly disappointing. This is because of the relentless growth of the central nervous system (CNS) and/or the systemic cancers, or their lethal complications. Advances in the understanding of the homing of cancer cells to the CNS, and of cance...

2016
Jong Sik Lee Kyung Ann Lee Kang Hoon Lee Sun Young Moon In Ae Kim Sung Jin Jeon Jae Ki Min Hee Joung Kim Kye Young Lee

We report on a 64-year-old man with leptomeningeal metastasis (LM) from an epidermal growth factor receptor (EGFR)-mutated adenocarcinoma of the lung. He was treated with paclitaxel, cisplatin. After completion of chemotherapy, he complained of headache, nausea, and vomiting. EGFR-mutated tumor cells were identified from the cerebrospinal fluid (CSF). Second-line therapy with gefitinib, methotr...

Journal: :AJNR. American journal of neuroradiology 1994
D J Schumacher R D Tien H Friedman

A patient had severe hydrocephalus and diffuse leptomeningeal enhancement on MR which mimicked leptomeningeal spread of a primary brain tumor. The leptomeningeal enhancement resolved completely after decompression of the hydrocephalus. Data suggest that the leptomeningeal enhancement is caused by vascular stasis induced by the hydrocephalus.

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