Leptospirosis is a common disease of livestock, pet many countries for cattle, dogs and swine but vaccination may animals and wildlife throughout the world. Sporadic cases and prove only partially effective due to generation of serovar outbreaks of the disease have been reported from USA, U.K, specific immunity, prevalence of several Leptospira serovars Australia, New Zealand, USSR and countrie...

Recent evidence based on the current epidemiological situation suggests that vaccines against canine leptospirosis in Europe should be directed against infection with Leptospira interrogans (sensu lato) serogroups Canicola, Icterohaemorrhagiae, Grippotyphosa and Australis. In the eight studies presented here, dogs were vaccinated with Nobivac L4 (MSD Animal Health), a new tetravalent inactivate...

CE Email comments/questions to [email protected], fax 800-556-3288, or log on to www.VetLearn.com Leptospirosis is a zoonotic disease of worldwide significance. It is caused by antigenically distinct serovars of the parasitic species Leptospira interrogans sensu lato, of which eight are most important to dogs and cats. The disease, which is caused by serovars most commonly incriminated (...

Stalheim, O. H. V. (University of Wisconsin, Madison) and J. B. Wilson. Leptospiral colonial morphology. J. Bacteriol. 86:482-489. 1963.-A sequence of apparent colonial types was observed with colonies of Leptospira pomona, L. canicola, L. icterohaemorrhagiae, and L. grippotyphosa in agar medium. Although some colonies of these serotypes had a different appearance initially, they eventually dev...

Numerous attempts have been made to control leptospirosis by using chemoprophylaxis, but with limited success. The present study was done investigate the antileptospiral potential of hexane, ethyl acetate and methanol extracts Zingiber zerumbet rhizomes. were assayed for activity broth microdilution method against Leptospira interrogans (serovar Batavie, Canicola, Australis) biflexa serovar Pat...

Little information is available regarding the duration of immunity achieved by Leptospira vaccination. The aim of this study was to assess in dogs the one-year protection induced by a leptospirosis vaccine against a Leptospira (L.) interrogans serovar icterohaemorrhagiae challenge. Six 8-9 week old dogs were immunised twice at a 3-week interval with a bivalent vaccine composed of inactivated ba...

The genomic structures of spirochete species are not well characterized, and genetic studies on these organisms have been hampered by lack of a genetic exchange mechanism in these bacteria. In view of these observations, pulsed-field gel electrophoresis was used to examine the genomes of Leptospira species. Live cells, prepared in agarose plugs, were lysed in situ, and the DNA was analyzed unde...

Leptospirosis is a re-emerging tropical infectious disease [1], is an important zooanthroponotic disease spread-worldwide [2]. The spirochetes of the genus Leptospira is responsible of human and animal leptospirosis characterized as mild febrile illness to severe multiorgan failure, especially pulmonary hemorrhage and renal failure [3]. Pathogenic leptospires are highly motile and invasive spir...