BACKGROUND Catheter ablation of ventricular tachycardia (VT) associated with structural heart disease is more difficult than ablation of idiopathic VT. The larger size of responsible reentrant circuits contributes to the difficulty in achieving an adequate ablation lesion with conventional techniques. Recently, cooling of the ablation electrode by saline irrigation has been shown to increase RF...

Background: Toll like receptors play a major role in immune responses against Leishmania parasites. Objective: To evaluate the efficacy of vaccination with live attenuated L. major and TLR4 agonist in protection against L. major infection. Methods: Attenuated L. major was prepared by continuous sub-culturing of the parasite. A total of 90 mice were assigned to 9 groups including 6 groups of BAL...

Background and aims. The correlation between morphology of giant cells in peripheral granulomas of the jaws and the aggressive behavior of the lesion is unknown. This study investigated the correlation between the histopathologic features with demographic, gross and radiographic findings in giant cell granulomas. Materials and methods. In this analytical study, data from 23 cases of central gia...

PURPOSE We investigated a newly developed bipolar and multipolar RF ablation system with an internally cooled electrode and resistance controlled power output in a standardized model of perfused ex vivo kidney tissue. MATERIALS AND METHODS RF energy was applied at different power levels (20, 30 and 60 W) for 1, 3, 5 and 9 minutes. Each treatment parameter was repeated 5 times. For the 20/30 W...

Ethanol-induced hepatic lesions were investigated in swine for in vivo use as a strain imaging animal model. Lesions (n = 25) were induced by injecting ethanol (doses 0.33 to 2.0 mL) directly into the surgically exposed liver at depths of 12, 15 or 25 mm. Lesions were imaged with a modified HDI 1000 scanner (Philips Medical Systems, Bothell, WA, USA). The elastograms (n = 91) characterized lesi...

the histopathologic diagnosis of orbital and ocular adnexal lymphoproliferative lesions is difficult, resulting controversy in classification, determining benignity or malignancy of them and treatment modality selection. we designed the following study to evaluate clinical, histopathologic and if necessary immunochemical features of them in decreasing indeterminate cases. the study includes 51 ...

introduction: striae distensae (sd) are a frequent skin condition for which treatment remains a challenge. the 1540-nm non-ablative fractional laser (star lux 500) has been shown to improve atrophic scars by increasing the amount of dermal collagen. to assess the safety and efficacy of the star lux 500 laser in the treatment of mature hypopigmented striae in persian people (striae alba). method...

this case is a 19-year-old soldier who suffered a combined elbow dislocation and posterior monteggia fracture and dislocation (type ii). the ulna fracture was managed by orif. the elbow dislocation was managed by closed reduction and immobilization in 900 flexion. the posteriorly dislocated radial head was kept reduced by a transarticular pin. after 6 months elbow and forearm motion was restric...

Lesion detection by MR imaging depends on the contrast-to-noise ratio of the voxels containing the lesion relative to those containing the background. When the lesion voxels are less than completely filled, the inherent contrast between lesion and background is modified by the filling factor. Lesion detection thus depends on lesion size, slice thickness, lesion position relative to slice, thick...