نتایج جستجو برای: levels of ifn γ
تعداد نتایج: 21206935 فیلتر نتایج به سال:
In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the role that CD4+ T-cell-driven inflammatory responses have in the pathogenesis of SMA, peripheral CD4+ T-cell populations and their intracellular production of pro-inflammatory...
چکیده زمینه و هدف:. بسیاری از عوامل می توانند در پیشرفت بیماری سل دخیل باشند، اما فاکتور های ژنتیکی میزبان مهمترین نقش را در پیشرفت این بیماری دارند. یکی از این فاکتورهای ژنتیکی، پلی مورفیسم ژنهای کد کننده ی سایتوکاین ها می باشد. مطالعات اخیر نشان می دهد که سایتو کاین هایی مانند IL-12 و IFN-γ نقش محوری را در تنظیم نوع، و میزان پاسخ های ایمنی در عفونت های مایکوباکتریومی بازی می کنند و موتاس...
The aim of the present study was to determine seroprevalence of Toxoplasma gondii infectionin stray cats and correlation with oocyst shedding and IFN-γ concentration. From April to August 2016, one hundred fifty-nine stray cats were captured from various localities in Mashhad area. The blood and fecal samples were collected from each cat. The serum samples were examined to detect antib...
Introduction: Leishmaniasis is one of the common diseases between humans and animals. The present study was to investigate the expression pattern of pro-inflammatory genes in different stages of cutaneous leishmaniasis progression in order to provide a standard framework for diagnosis of various stages of the disease. Methods: In this experimental study, 2×106 Leishmania major were injected in...
background & aim: multiple sclerosis(ms) is the most common inflammatory disease of central nervous system which is caused by an autoimmune process leading to destruction of myelin sheath. in this disease, cd4+ t–lymphocytes, mostly of th1 phenotype, play important roles in destruction of neuronal tissues. because of the probable etiologic participation of ebv virus in immunopathogenesis of ms...
In order to determine the effect of B7‑H4 on the development of human hepatocellular carcinoma (HCC), the expression levels of B7‑H4 were evaluated using reverse transcription‑polymerase chain reaction and flow cytometry in HL‑7702 and Huh7 cells. B7‑H4 protein expression levels were analyzed using western blotting and immunohistochemistry in HCC tissues collected from patients and from a mouse...
PURPOSE To investigate the profile of T-helper type 17 (Th17) cell-related cytokines (interleukin-23 [IL-23], IL-27, IL-17 and interferon-γ [IFN-γ]) in postoperative inflammation in patients with Behcet disease (BD) after cataract surgery. METHODS Serum was collected from seven BD patients with complicated cataract, and from nine controls with uncomplicated cataract, before cataract surgery, ...
Abstract Background and Objectives Antibody against RhD antigen is important in blood transfusion and clinical medicine. Therefore, in this study, the effective factors in the optimization of in vitro immunization to achieve immunized lymphocytes that produce antibodies were evaluated to obtain antibodies against RhD antigen in the culture medium. Materials and Methods In an experimental study...
IFN-γ is a key cytokine in antituberculosis (TB) defense. However, how the levels of its secretion affect M. tuberculosis (Mtb) infection is not clear. We have analyzed associations between IFN-γ responses measured in QuantiFERON®-TB Gold In-tube (QFT) assay, TB disease severity, and Mtb infection activity. TB severity was evaluated based on the results of radiological, microbiological, and cli...
زمینه و اهداف: میگرن شایع ترین نوع سردرد است. به طوریکه %12-15 مردم جهان از آن رنج می برند. یکی از جدیدترین یافته ها وجود ارتباط بین عفونت هلیکوباکترپیلوری و انواع میگرن است. هدف از این مطالعه تعیین تیتر آنتی بادی علیه هلیکوباکترپیلوری در بیماران مبتلا به میگرن در مقایسه با افراد سالم بود.روش بررسی: این مطالعه به صورت مورد - شاهدی بر روی بیماران مراجعه کننده به درمانگاه مغز واعصاب و مطب های خصو...
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