Emerging evidence continues to support the functional importance of extracellular matrix (ECM) proteins in cellular signaling. In mineralizing tissues, including bone, cartilage, and vasculature, ECM proteins not only provide the microenvironment for propagation of crystal growth but also support and transmit mechanical cues to the cells, and these cues govern many aspects of cell function, inc...

at present, new tendencies in international commercial arbitration try to delocalize and gives more independence to arbitration, from national laws. the ultimate degree of this independency is demonstrated in lex mercatoria theory. in recent years this theory has been gone beyond the frontiers of pure theory and entered into the national laws of some countries such as netherlands, france and in...

We study Hilbert functions of graded ideals using lex ideals.

OBJECTIVE The incidence of pulmonary embolism (PE) and leg deep vein thrombosis (DVT) has increased in recent years in association with aging and an increase in the number of bedridden individuals. We developed an active in-bed leg exercise apparatus labeled the Leg Exercise Apparatus (LEX) for DVT prevention. We compared the effect of leg exercises performed using the LEX to conventional activ...

PURPOSE This investigation examined the effect of 6 months of high- or low-intensity resistance exercise (REX) on bone mineral density (BMD) and biochemical markers of bone turnover in adults aged 60-83 yr. METHODS Sixty-two men and women (68.4 +/- 6 yr) were stratified for strength and randomly assigned to a control (CON, N = 16), low-intensity (LEX, N = 24), or high-intensity (HEX, N = 22) ...

Haemophilus parasuis is a common opportunistic pathogen known for its ability to colonize healthy piglets and causes Glässer's disease. The lipooligosaccharide (LOS) of H. parasuis is a potential virulence-associated factor. In this study, two putative glycosyltransferases that might be involved in LOS synthesis in H. parasuis SC096 were identified (lgtB and lex-1). Mutants were constructed to ...

DC-specific ICAM3-grabbing non-integrin (DC-SIGN), which is expressed on DCs, can interact with a variety of pathogens such as HIV-1, hepatitis C, Ebola, cytomegalovirus, Dengue virus, Mycobacterium, Leishmania, and Candida albicans. We demonstrate that human milk can inhibit the DC-SIGN-mediated transfer of HIV-1 to CD4+ T lymphocytes as well as viral transfer by both immature and mature DCs. ...