نتایج جستجو برای: lifr
تعداد نتایج: 218 فیلتر نتایج به سال:
IntroductionCongenital anomalies of the kidney and urinary tract (CAKUT) are predominant cause chronic disease (CKD) need for replacement therapy (KRT) in children. Although more than 60 genes known to CAKUT if mutated, a genetic etiology is detected on average only 16% unselected cases, making testing unproductive.MethodsWhole-exome sequencing (WES) was performed 100 patients diagnosed first 1...
Abstract The average fat mass in adults increases dramatically with age, and older people often suffer from visceral obesity related adverse metabolic disorders. Unfortunately, how aging leads to accumulation is poorly understood. It known that cell (adipocyte) turnover very low young mice, similar humans. Here, we find mice mimic age-related expansion In vivo lineage tracing shows massive adip...
Progenitor Leydig cells are derived from stem cells. The proliferation and differentiation of progenitor Leydig cells significantly contributes to Leydig cell number during puberty. However, the regulation of these processes remains unclear. The objective of the present study was to determine whether luteinizing hormone (LH) or androgen contributes to the proliferation and differentiation of pr...
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