the important role of reperfusion therapies in the treatment of acute myocardial infarction is well documented. however, reperfusion therapies can initiate inflammatory response and may damage the myocardium. the purpose of current study was to compare the effects of percutaneous coronary intervention and thrombolytic therapy on inflammatory markers in the setting of st elevation myocardial inf...

analysis of  receptor–ligand  interactions  in  the  context  of  diseases  necessitates  to understand how hla–kir genotypes function in diseases. although cd56+  lymphocytes are derived from multiple lineages, they share a functional association with immunosurviellance and antimicrobial responses. the present study aimed to determine whether kir phenotype in cd56 lymphocytes and corresponding...

conclusions saturated fatty acids (sfas) served as a potential ligand for tlr4 and activated tlr4 signaling pathway, which might be involved in the pathogenesis. thus, sfas can accelerate the mechanism of inhibiting hbv replication in chb with nafld. objectives this study aimed to investigate whether the tlr4-mediated innate immunity stimulates the pathogenesis of chb in patients with nafld and...

background: m2000 is a newly designed and safe non-steroidal anti-inflammatory drug (nsaid). the aim of this study was to assess the effects of m2000 on expression levels of suppressor of cytokine signaling-1 (socs-1) and src homology-2 domain-containing inositol-5’-phosphatase 1 (ship1) proteins via toll-like receptor (tlr) 2/microrna-155 pathway. methods: hek293 tlr2 cell line and peripheral ...