نتایج جستجو برای: linked dextran microspheres

تعداد نتایج: 256278  

Journal: :European Journal of Pharmaceutics and Biopharmaceutics 2021

Active self-encapsulation (ASE) is a recently developed post-loading method based on absorption of (positively charged) proteins in microporous PLGA microspheres loaded with negatively charged polysaccharides (trapping agents). The aim this study was to investigate ASE for simultaneous loading and controlled release multiple growth factors. For purpose, vascular endothelial factor (VEGF), fibro...

Journal: :Biomaterials 1998
A K Andrianov J Chen L G Payne

A new method of preparing ionically cross-linked polyphosphazene hydrogel microspheres which enables effective control over microsphere size distribution has been developed. The synthesized microspheres can be used in protein delivery and, especially, as vaccine delivery vehicles. A new technique utilizes the ability of aqueous solutions of poly[di(carboxylatophenoxy)phosphazene] (PCPP) to form...

2012
V. Bocharova O. Zavalov K. MacVittie M. A. Arugula N. V. Guz M. E. Dokukin J. Halamek I. Sokolov V. Privman E. Katz

The present study aims at integrating drug-releasing materials with signal-processing biocomputing systems. Enzymes alanine transaminase (ALT) and aspartate transaminase (AST)—biomarkers for liver injury—were logically processed by a biocatalytic cascade realizing Boolean AND gate. Citrate produced in the system was used to trigger a drugmimicking release from alginate microspheres. In order to...

Journal: :Asian Journal of Pharmaceutical and Clinical Research 2020

Journal: :iranian journal of pharmaceutical research 0
reza masaeli dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran teherh sadat jafarzadeh kashi dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran rasoul dinarvand nanotechnology research centre, faculty of pharmacy, tehran university of medical sciences, tehran 1417614411, iran mohammadreza tahriri dental biomaterials department, school of dentistry, tehran university of medical sciences, tehran, iran vahid rakhshan department of anatomy, dental branch, islamic azad univesity mehdi esfandyari-manesh nanotechnology research center,tehran university of medical sciences, tehran, iran

microspheres formulated from poly (d,l-lactic-co-glycolide) (plga), a biodegradable polymer, have been extensively evaluated as a drug delivery system. in this study, the preparation, characterization and drug release properties of the plga microspheres were evaluated. simvastatin (sim)-loaded plga microspheres were prepared by oil-in-water emulsion/solvent evaporation method. the microspheres ...

Journal: :iranian journal of pharmaceutical research 0
r dinarvand e rahmani e farbod

a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

Journal: :Journal of immunoassay & immunochemistry 2015
Zhen-ming Xie Lin Yu Li-sha Fang

The enzyme-linked immunosorbent assay (ELISA) is a potential tool for the determination of dextran. In this study, dextran neoglycoprotein antigens were prepared by Reductive Amination method, and were confirmed by SDS-PAGE and free amino detection. The impact factors such as different oxidation degree of dextran, the conjugate reaction time to BSA were investigated. The best preparation condit...

Journal: :Food research international 2016
Siriwan Nawong Ratchadaporn Oonsivilai Nantakorn Boonkerd Lisbeth Truelstrup Hansen

Dietary intake of probiotic bacteria has been shown to impart health effects, however, maintaining viable cells in foods and during passage of the adverse conditions in the upper gastro-intestinal tract is often a problem. The objective of this research was to develop and characterize novel food-grade phase-separated gelatin-maltodextrin (G-MD) microspheres, where the gelatin was cross-linked w...

Journal: :iranian journal of pharmaceutical sciences 0
fatemah atyabi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran afsaneh mohammadi department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran rassoul dinarvand department of pharmaceutics, faculty of pharmacy, tehran university of medical sciences, tehran, iran

the purpose of this study was to prepare and characterize nimodipine loaded microspheres using ethyl cellulose (ec) as a carrier polymer through an emulsion solvent evaporation method. these evaluations characterized the pattern of drug release from prepared microspheres. nimodipin loaded microspheres were prepared using an emulsification solvent evaporation method. the effect of process variab...

Journal: :iranian journal of pharmaceutical research 0
j patel d patel j raval

the purpose of this research was to formulate and systemically evaluate in-vitro and in-vivo performances of mucoadhesive propranolol hydrochloride microspheres for its potential use in the treatment of hypertension, myocardial infraction and cardiac arrhythmias. propranolol hydrochloride mucoadhesive microspheres, containing carbopol-934p as mucoadhesive polymer and ethyl cellulose as carrier ...

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