نتایج جستجو برای: liver fibrosis
تعداد نتایج: 410943 فیلتر نتایج به سال:
Hepatocellular carcinoma (HCC) occurs in patients with chronic liver damage, inflammation and cirrhosis. The facilitators involved increasing the HCC risk damaged are yet to be discovered. Diet lifestyle have a profound effect on HCC. term “gut axis” describes bidirectional relationship between gut, which both anatomically functionally related. Chronic damage is characterised by increased intes...
Drug Delivery In article number 2212206, Ying Zhao, Xiaolong Qi, Guangjun Nie, and co-workers propose a liver sinusoid capillarization hepatic stellate cells activation combined regulation strategy for fibrosis treatment. Liver fenestrae restoration enhances the transport efficiency of nanomedicine through wall, which represents promising approach
Chronic liver disease is a progressive deterioration of hepatic functions and continuous process inflammation, destruction, regeneration parenchyma, resulting in fibrosis cirrhosis [...]
Liver fibrosis is a common pathway leading to cirrhosis, which is the final result of injury to the liver. Accurate assessment of the degree of fibrosis is important clinically, especially when treatments aimed at reversing fibrosis are being evolved. Liver biopsy has been considered to be the "gold standard" to assess fibrosis. However, liver biopsy being invasive and, in many instances, not f...
PURPOSE To investigate the utility of dynamic contrast-enhanced MRI (DCE-MRI) with Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) for detecting liver fibrosis induced by carbon tetrachloride (CCl4) in rats. METHODS This study was approved by the institutional animal care and use committee. Liver fibrosis in rats was induced by intraperitoneal injection of 1 mL/kg 50...
INTRODUCTION: Hepatic fibrosis is a wound-healing response to multiple types of chronic liver disease or injury. Cirrhosis, the end-stage of liver fibrosis, is a major cause of death due to its association with hepatocellular carcinoma and complicated portal hypertension. Accurate discrimination of advanced fibrosis and cirrhosis from mild fibrosis in patients with chronic liver disease is esse...
AIM To investigate whether serum interleukin (IL)-34 levels are correlated with hepatic inflammation and fibrosis in patients with chronic hepatitis B virus (HBV) infection. METHODS In this study, serum IL-34 levels were assessed by enzyme-linked immunosorbent assay in 19 healthy controls and 175 patients with chronic HBV infection undergoing biopsy. The frequently used serological markers of...
at present, liver transplantation remains the only curative option for the patients with cirrhosis and end-stage liver diseases. the survival rate and recurrent diseases remain the major issues in the patient post-transplantation. unani medicine is one of the oldest traditional systems of medicine which has been treating chronic liver diseases and cirrhosis (talayyaful-kabid) for centuries. the...
In this study, the therapeutic effect of Mel-incubated Adipose-derived mesenchymal stem cells (ADSCs) on CCl4-induced hepatic fibrosis was investigated. Mice with were intraperitoneally injected 8% CCl4 twice a week for 4 weeks. Starting from 5, mice in ADSC group and + Mel 1 mL PBS cell suspension containing × 106 ADSCs or pretreated 50 nM 2 consecutive Results: model group, severe histopathol...
With increasing innovations aimed at the treatment of chronic liver disease (CLD), the precise staging of liver fibrosis is important to help establish efficacious management of disease activity in each patient. The development of biomarkers capable of non-invasive staging of fibrosis in the liver is challenging as fibrogenesis is a part of the normal wound healing response. There is an array o...
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