BACKGROUND: Locally advanced colorectal cancers form a distinct subgroup where contiguous organs could be involved without distant metastases and so may be amenable to curative surgical resection. It was our objective to report our experience in treating six such patients with operable locally advanced colorectal carcinomas. METHODS: We retrospectively reviewed the case notes of 47 patients who...

BACKGROUND Renal cell carcinoma accounts for approximately 3% of adult malignancies and over 90% of primary renal tumors. Recurrence rates for patients with locally advanced renal cell carcinoma (LARCC) remain high. METHODS The authors review literature regarding prognostic factors, potential biomarkers, surgical strategies, and adjuvant therapy trials for patients with LARCC. RESULTS Molec...

Introduction: The current standard of treatment for locally advanced cancer cervix is cisplatin based concurrent chemo radiation therapy followed by brachytherapy. Concurrent radiotherapy causes acute hematological toxicities, which in turn leads to prolongation therapy. Objective: main purpose our study, was analyze the toxicity cervical patients undergoing or Materials and Methods: This a hos...

objective(s): expression of her2 in gastric carcinoma has direct prognostic and therapeutic implications in patient management. the aim of this study is to determine whether a relationship exists between standardized uptake value (suv) and expression of her2 in advanced gastric carcinoma. methods: we analyzed the 18f-fdg pet/ct results of 109 patients that underwent gastrectomy for advanced gas...

Nowadays there is insufficient evidence that pre-treatment surgical para-aortic lymph node assessment for locally advanced cervical cancer is beneficial. No randomized trials address this issue, and therefore definitive recommendations cannot be made [1]. The uncertainty regarding survival impact of pre-treatment para-aortic lymph node assessment results in different treatment alternatives, in ...