an inhibitory modulator of cholinergic and noradrenergic neurotransmission (Miller et al., 1999; Van Hoomissen et al., 2004; Landry et al., 2005; Hobson et al., 2006). Gal is co-localized with norepinephrine (NE) in several regions of the brain, such as locus coeruleus, bed nucleus of the stria terminalis, amygdala, cortex and hippocampus (Hokfelt et al., 1998; Kozicz, 2001; Xu et al., 2001; Ho...

By means of extracellular recordings, individual norepinephrine-containing neurons in the locus coeruleus of unanesthetized behaviorally responsive rats and squirrel monkeys were found to respond to specific sensory and behavioral conditions. In rats, distinct clusters of action potentials followed the presentation of various nonnoxious auditory, visual, or somatosensory stimuli at latencies of...