Title: p53 expression in patients with ulcerative colitis associated with dysplasia and carcinoma: a systematic meta-analysis Authors: Xiaohong Lu ([email protected]) Yuanjie Yu ([email protected]) Shiyun Tan ([email protected]) Version: 1 Date: 18 Jun 2017 Author’s response to reviews: Response: p53 expression in patients with ulcerative colitis associated with dysplasia and carcino...

BACKGROUND Today's standard treatment of advanced-stage ovarian cancer, including surgery followed by a paclitaxel-platinum-based chemotherapy, is limited in efficacy. Recently, we could show that radioimmunotherapy (RIT) with (177)Lu-labelled anti-L1 cell adhesion molecule (L1CAM) monoclonal antibody chCE7 is effective in ovarian cancer therapy. We investigated if the efficacy of anti-L1CAM RI...

Phosphonic acids labeled with beta-emitting radionuclides are promising radiopharmaceutical drugs for palliative therapy of bone metastases. Currently, the possibility using a new osteotropic compound N,N,N’,N’-ethylenediaminetetrakis (methylene phosphonic acid) lutetium-177 (177Lu-EDTMP) is being studied. The aim work to develop compartment mathematical model kinetics 177Lu in body laboratory ...

Neuroendocrine tumors (NETs) are tumors originated from neuroendocrine cells in the body. The localization and the detection of the extent of NETs are important for diagnosis and treatment, which should be individualized according to the tumor type, burden, and symptoms. Molecular imaging of NETs with high sensitivity and specificity is achieved by nuclear medicine method using single photon-em...

We report a rare case of a laparoscopic splenectomy performed for a carcinoid metastasis. The patient represented with pleuritic left-sided chest pain from pleural deposits 9 years following resection of a primary lung carcinoid tumour. They were found to have a 4.7 cm splenic lesion on CT with a probable left acetabular metastasis demonstrated on Gallium PET scan. The patient underwent laparos...

Cerium doped lutetium silicate powders were prepared by solegel process with different cerium concentrations (0, 0.01 and 0.03 mol%). The synthesized lutetium silicate powders were investigated by X-ray diffraction (XRD), TG-DTA, SEM, and Photoluminescence excitation and emissions. The crystallization of lutetium silicate is observed at 1.073 C in S2 (and S3: 1.058 C) sample. The formation of l...