نتایج جستجو برای: lymphoid organs

تعداد نتایج: 98857  

Journal: :Proceedings of the National Academy of Sciences 1991

Journal: :The European respiratory journal 2021

A key principle of emergency management is establishing an incident command centre. That's where information gathered via integrated communications, plans are formulated, responsibilities assigned, and resources deployed. The immune system deals with microbial threats by this same approach, using organised lymphoid tissues. At the early stages infections, conventional dendritic cells (cDCs) tra...

Journal: :JCI insight 2017
Nataliya P Buxbaum Donald E Farthing Natella Maglakelidze Martin Lizak Hellmut Merkle Andrea C Carpenter Brittany U Oliver Veena Kapoor Ehydel Castro Gregory A Swan Liliane M Dos Santos Nicolas J Bouladoux Catherine V Bare Francis A Flomerfelt Michael A Eckhaus William G Telford Yasmine Belkaid Remy J Bosselut Ronald E Gress

Hematopoietic stem cell transplantation (HSCT) offers a cure for cancers that are refractory to chemotherapy and radiation. Most HSCT recipients develop chronic graft-versus-host disease (cGVHD), a systemic alloimmune attack on host organs. Diagnosis is based on clinical signs and symptoms, as biopsies are risky. T cells are central to the biology of cGVHD. We found that a low Treg/CD4+ T effec...

Journal: :Fukushima journal of medical science 2008
Atai Satoh Takuro Saito Yoshihiro Sato Takao Tsuchiya Akira Kenjo Takashi Kimura Ryuzo Kanno Hiroyuki Suzuki Michio Kogure Yutaka Hoshino Mitsukazu Gotoh

UNLABELLED Bone marrow (BM) cells are considered the source of stem cells for various organs. However, how quickly BM cells can penetrate and constitute lymphoid organs remains elusive. In the present study, we addressed this issue in a model using genetically-labeled syngeneic BM transplantation (BMT). METHODS Donor BM cells were obtained from "green mice", transgenic mice with enhanced GFP....

Journal: :Archives of histology and cytology 2010
Kenjiro Matsuno Hisashi Ueta Zhou Shu Xu Xue-Dong Yasushi Sawanobori Yusuke Kitazawa Yu Bin Masaki Yamashita Changde Shi

Immune cell trafficking in the secondary lymphoid organs is crucial for an effective immune response. Recirculating T cells constantly patrol not only secondary lymphoid organs but also the whole peripheral organs. Thoracic duct lymphocytes represent an ideal cell source for analyzing T cell trafficking: high endothelial venules (HEVs) allow recirculating lymphocytes to transmigrate from the bl...

2011
Ruben Merino Hilda Villegas Jose A. Quintana Norma Calderon

Virulent Newcastle disease has threatened the Mexican poultry industry since 1946. Two Mexican virulent strains belonging to the Chimalhuacan (Quail2006) and Torreon (Chicken2000) lineages of genetic group V, as well as the ancient Mexican strain named Queretaro and a Beaudette C-like US strain (genotype II) were tested by pathogenesis analysis in commercial 5 weeks old broiler chickens, compar...

Journal: :Frontiers in Immunology 2023

Tertiary lymphoid structures (TLSs) are clusters of cells with an organization that resembles secondary organs. Both share common developmental characteristics, although TLSs usually appear in chronically inflamed non-lymphoid tissues, such as tumors. contain diverse types immune cells, varying degrees spatial represent different stages maturation. These support both humoral and cellular respon...

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