Primary progenitor tenocytes are diploid cells that may be cultured in vitro and therapeutically used for allogeneic musculoskeletal regenerative medicine. Firstly, technical aspects of cell banking, biotechnological manufacturing, extensive preclinical characterization data have confirmed FE002-Ten primary safely considered human cytotherapeutic use (e.g., tissue engineering products, standard...

A commercial casein hydrolysate was microencapsulated in liposomes produced with non-purified soy lecithin, cryoprotected with two different disaccharides and lyophilized. The encapsulation efficiency of casein hydrolysate ranged from 30 to 40%. The powders were analyzed by differential scanning calorimetry (DSC), scanning electron micrography (SEM), infrared spectroscopy (FTIR) and wide angle ...

A major problem of current vaccines is storage stability, often requiring strict maintenance of cold chains. In the course of the eradication of smallpox, a freezedried vaccinia virus (Dryvax), which proved to be very stable, was used to overcome this limitation. However, Dryvax needs to be reconstituted before usage and is administered using a bifurcated needle, procedures that pose a number o...

Methanolic extract from lyophilized roots of Impatiens glandulifera Royle was analyzed by high performance liquid chromatography using DAD and FLD detection and this revealed one dominant highly fluorescent very unstable substance. The stability of this derivative is strongly dependent on the plant material drying procedure and extraction procedure used. The structure of the substance was estab...

the purification and identification of reduced antibody fraction by spectrophotometer method; mass of Anti-CEA and MDP; time and temperature of lyophilized method. The best conditions for lyophilized kits were selected and the labelling efficiency was determined using ascending paper chromatography on Whatman 3MM paper and TLC-SG in 0.9 % saline and methyl ethyl ketone as a solvent. This work b...

The purpose of the present study was to develop stable lyophilized formulation peginterferon alfa-2b which is acquiescent short lyophilization process. evaluates effect buffering components and cryoprotectant(s) on depegylation in combination with Finally, a process identified can produce pharmaceutical form without any during long-term storage. Formulations were analyzed mainly for by HP-size ...

PURPOSE According to regulations from the Ministry of Food and Drug Safety in Korea, additional safety information on the use of Rotarix™ vaccine (RIX4414; GSK, Belgium) in ≥3000 evaluable Korean infants was required following vaccine registration. In order to comply with these regulations, we conducted a 6-year open, non-comparative, multicenter post-marketing surveillance (NCT00750893). MET...

A new formulation of dry fermented sausage, including ingredients that improve the nutritional and health benefits of this type of product is presented. Se yeast (2g/kg), iodized salt (26g/kg), linseed:algae (3:2) emulsion (62.5g/kg), and lyophilized water extract of Melissa officinalis L. as a source of natural antioxidants (686mg/kg), yielded dry fermented sausages with technological and sens...