نتایج جستجو برای: lyta
تعداد نتایج: 205 فیلتر نتایج به سال:
Loss-of-function mutations in the following seven pneumococcal genes were detected and analyzed: pspA, spxB, xba, licD2, lytA, nanA, and atpC. Factors associated with these mutations included (i) frameshifts caused by reversible gain and loss of single bases within homopolymeric repeats as short as 6 bases, (ii) deletions caused by recombinational events between nontandem direct repeats as shor...
Polyamines are small cationic molecules that have far-reaching roles in biology. In the case of pathogenic bacteria, these functions include those central to their pathogenesis. Streptococcus pneumoniae is a major bacterial pathogen, causing a diverse range of diseases that account for significant morbidity and mortality worldwide. In this work, we characterize the polyamine biosynthetic pathwa...
Prevalence of pneumococcal serotypes in carriage and disease has been described but absolute serotype colonisation densities have not been reported. 515 paediatric nasal swab DNA extracts were subjected to lytA qPCR and molecular serotyping by microarray. Absolute serotype densities were derived from total pneumococcal density (qPCR cycle threshold and standard curve) and relative abundance (mi...
Streptococcus pneumoniae is one of the common causes disease in children like pneumonia, otitis and meningitis. Pneumococci colonize asymptomatically nasopharynx could cause severe life-threatening illnesses. Since 2010, 10-valent pneumococcal conjugate vaccine (PCV-10) has been included Bulgaria for routine immunization from 6 weeks to 2 years. For period 2011-2019 coverage with it considered ...
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