A nanoparticle (NP) was developed to target choroidal neovascularization (CNV) via topical ocular administration. The NPs were prepared through conjugation of internalizing arginine-glycine-aspartic acid RGD (iRGD; Ac-CCRGDKGPDC) and transactivated transcription (TAT) (RKKRRQRRRC) peptide to polymerized ethylene glycol and lactic-co-glycolic acid. The iRGD sequence can specifically bind with in...

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

recent progress in nanotechnology and electrochemical methods can be applied to fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. here we appliedcathodic electrochemical deposition (ced) as an efficient and effective tactic for synthesisand double coating of surface of superparamagnetic iron oxide nanoparticles (spions). in first step, bare fe3o4 n...

Magnetic nanoparticles are the good choice for using in MRI as the contrast agent. Iron oxide particles such as magnetite (Fe3O4) or its oxidized form maghemite (γ-Fe2O3) are the most commonly employed in biomedical applications. In this study, we synthesized and optimized the preparation of chitosan manganese-ferrite nanoparticles (CMn-Fe nps) and evaluated its ability for the mice macrophage ...

The application of Pd/Fe3O4 nanoparticles (NPs) for the adsorption of sulfathiazole from urine samples prior to high performance liquid chromatography-ultraviolet detection was studied. Pd/Fe3O4 NPs were synthesized using plant extract. Possible impact parameters in the extraction process such as the magnetic adsorbents amount, extraction time, sample pH and desorption conditions were investiga...

The combination of radiotherapy (RT) and photothermal therapy (PTT) has been considered an attractive strategy in cervical cancer treatment. However, it remains a challenge to simultaneously enhance the radio-sensitivity of tumor tissue, develop tumor tissue-focused radiation therapies and combine dual therapeutic modalities. In this study, core-shell type magnetic gold (Fe₃O₄@Au) nanoparticles...

Magnetic resonance imaging (MRI) has been widely used to diagnose various diseases. As a positive MRI contrast agent, gadolinium oxide (Gd2O3) is the most promising one due to its paramagnetism and good biocompatibility. However, post-modification on hydrophobic Gd2O3 nanoparticles (NPs) often yield water soluble nanocomposites with some problems: particles aggregation which reduces the number ...

Superparamagnetic iron oxide nanoparticles (NPs) are used in a rapidly expanding number of research and practical applications in the biomedical field, including magnetic cell labeling separation and tracking, for therapeutic purposes in hyperthermia and drug delivery, and for diagnostic purposes, e.g., as contrast agents for magnetic resonance imaging. These applications require good NP stabil...

Magnetic nanoparticles are of great importance particularly in the field of biomedicine as well as nanotechnology and nano materials science and technology. Here, we synthesise magnetic alloy-filling carbon nanoparticles (MA@C NPs) via the following two-step procedure; (1) Irradiation of a laser beam of 266 nm wavelength into super-critical benzene, in which both ferrocene and cobaltocene are d...

Monodisperse Fe3O4 nanoparticles (NPs) with narrow size distribution are synthesized by a high-temperature solution-phase method. The diameter of the as-synthesized NPs is tuned from 2 to 14 nm by varying the reaction conditions. Highly ordered superlattice structures of the Fe3O4 NPs with areas extending over 0.8 microm x 0.7 microm have been successfully obtained. The magnetic properties are ...