نتایج جستجو برای: major thalassaemia

تعداد نتایج: 620506  

Journal: :British Journal of Ophthalmology 1983

2009
Ali T. Taher Khaled M. Musallam Maria D. Cappellini

Our understanding of the molecular and pathophysiological mechanisms underlying the disease process in patients with thalassaemia intermedia (TI) has substantially increased over the past decade. TI encompasses a wide clinical spectrum of beta-thalassaemia phenotypes. Some TI patients are asymptomatic until adult life, whereas others are symptomatic from as young as 2 years of age. A number of ...

Journal: :Blood cells, molecules & diseases 2013
Sasikala Suresh Christopher Fisher Helena Ayyub Anuja Premawardhena Angela Allen Ashok Perera Dayananda Bandara Nancy Olivieri David Weatherall

The α-globin genes were studied in nine families with unexplained hypochromic anaemia and in 167 patients with HbE β thalassaemia in Sri Lanka. As well as the common deletion forms of α(+) thalassaemia three families from an ethnic minority were found to carry a novel form of α(0) thalassaemia, one family carried a previously reported form of α(0) thalassaemia, --(THAI), and five families had d...

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