Abstract Background Cerebral neoplasm arises from brain, spinal cord and meningeal cells. Not only malignant cerebral neoplasm also benign tumor could lead to death due to mass effect on vital structures. Access to these tumors is difficult, and MRI and CT scan could be helpful in determining anatomical location of tumors and distinction of malignant from benign. Objective For better and ea...

Background & Objective: This study was designed for the first time for the detection of mutant BRAF V600E and its correlation with clinicophathologic features in a sample of Iranian patients with pathologically proved pigmented skin neoplasms.Methods: 82 paraffin-embedded blocks, including melanocytic nevi, malignant melanoma, Basel cell carcinoma, and sq...

BACKGROUND To determine the frequency of various histologic types of primary solid malignant neoplasms in males and females, in our practice, in a large series of surgical biopsies. METHODS A retrospective study of 20,000 consecutive surgical biopsies in the section of Histopathology, Aga Khan University Hospital (AKU), Karachi, in 2004. RESULTS Squamous cell carcinoma of oral cavity was th...

AIM The aim of the present study is to establish the relative frequency and distribution of benign and malignant epithelial neoplasms of salivary glands in the Pathology and Cytology Laboratory, STUDY DESIGN Historic cohort. MATERIAL AND METHOD in the state of Sergipe, during the period 1980-1999. The neoplasms were individualized by gender, age, race of the patients, anatomic localization ...

Malignant melanoma can metastasize widely and vary significantly in its histological appearance; it rarely presents as a deep-seated mass without an obvious primary site elsewhere. Malignant peripheral nerve sheath tumor (MPNST) is a high-grade sarcoma characterized by conventional and epithelioid subtypes. MPNST can demonstrate heterologous differentiation, usually in the form of osteosarcomat...

Malignant melanoma is an aggressive neoplasm affecting the oral cavity. It has the most biologically unpredictable behavior. The tumors can be locally invasive or metastasize to other parts of the body. Pre-existing pigmentations can evolve into malignant melanomas in about 30% of the cases. Hence, early detection of pigmented lesions of undetermined origin is important and should be routinely ...

Primary small cell neuroendocrine carcinoma (SCNEC) is a rare high-grade malignant neoplasm with differentiation derived from the urothelium. Herein, we report case which presented symptomatic anaemia secondary to haematuria, complicated acute kidney injury following obstructive uropathy caused by SCNEC, along discussion of clinical presentation, radiological imaging and pathological findings d...

Malignant cylindroma (cylindromatous carcinoma, cylindrocarcinoma) is the malignant counterpart of benign cylindroma. It is a rare neoplasm, more often developing in the setting of multiple preexisting benign neoplasms. Herein we present an additional case of malignant transformation of the cylindroma diagnosed in an 83-year-old patient with known Brooke-Spiegler syndrome.

OBJECTIVE To identify clinical and ultrasonographic features that may help in predicting malignant tumors in patients with a diagnosis of follicular neoplasm on findings from fine-needle aspiration cytology (FNAC) because FNAC diagnosis of follicular neoplasm does not differentiate a benign tumor from a malignant tumor. DESIGN Prospective study of 98 patients having a diagnosis of follicular ...

Calcifying odontogenic cyst (COC) is a unique odontogenic lesion with combined features of a cyst and neoplasm.  This lesion shows a great diversity in its clinicopathological behavior.  It may become aggressive and rarely malignant.  This case is an aggressive COC of the maxilla in a young male patient which recurred after several radical surgical excisions.  Eventually invading the cranium, t...