a 41 year old woman was referred to our center because of a left breast mass lesion of about two months duration. routine pathologic examination of the mass revealed a .neoplastic tissue composed of large ovoid cells with clear cytoplasm arranged in broad sheets that were separated by thin bundles of connective tissue. immunohistochemically tumor cells express smooth muscle actin, cytokeratin, ...

osteosarcoma is a primary malignant tumor of bone, which can involve jaws. this article reviews osteosarcoma of the jaws referred to the department of oral pathology, dental faculty of tehran university of medical sicences and pathology department of cancer institiute in imam khomeini hospital during 30 years from 1349 to 1378 and also reviews jaw osteosarcoma in english literature. the purpose...

Extrarenal rhabdoid tumors (ERRTs) are extremely rare neoplasms; of these, colorectal ERRTs are the most rare, and only nine cases have been previously described in the English language literature. The current study reports the pathological features of a case of poorly differentiated cecal adenocarcinoma with prominent rhabdoid feature, which was combined with mucinous cystadenoma of the append...

Malignant rhabdoid tumor (MRT) is a rare and highly aggressive tumor presenting in the kidney and soft tissue in childhood. However, effective treatment for MRT has not been established. We investigated the antitumor effect of etodolac, a selective cyclooxygenase-2 inhibitor, on MRT cells in vitro using the MRT cell line FRTK-1. Etodolac induced apoptosis of FRTK-1 cells through activation of c...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Malignant melanomas display a wide variety of morphologic patterns. 1 Melanomas with rhabdo...

Malignant rhabdoid tumors are highly aggressive neoplasms that were initially described in the kidneys of children as a rare variation of Wilms tumors with a rhabdomyosarcomatoid pattern and particularly poor prognosis. Subsequently, tumors with histologically similar characteristics were found in other locations, and classified as extrarenal malignant rhabdoid tumors (EMRT). These neoplasms ar...

Deepti Dhavaleshwar, MD; Kofi Clarke, MD, FRCP, Allegheny Health Network, Allegheny General Hospital, Division of Gastroenterology, Pittsburgh, PA Ten cases of primary colonic malignant extrarenal rhabdoid tumors (MERT) have been reported. We report a case in a 31-year-old female who presented with abdominal pain, nausea and vomiting. Her initial evaluation was significant for leukocytosis and ...

Atypical teratoid/rhabdoid tumors (AT/RTs) are rare, highly malignant central nervous system tumors that predominantly occur in young children. A 22-year-old woman presented with a 4-year history of relapsing tinnitus and gradual hearing loss. Neuroimaging revealed an enhanced intrinsic left internal auditory canal mass. The patient underwent radiotherapy treatment. Three years later, the tumor...

The author presents a unique case of multiple cytokeratin-negative malignant tumors consisting only of rhabdoid cells in the renal pelvis. A 54-year-old man complained of hematuria. A transurethral endoscopic examination revealed multiple papillary tumors, and transurethral resection of the bladder tumors was performed. Pathologically, they were ordinary papillary urothelial transitional cell c...

Rhabdoid colorectal carcinomas are very rare and only 10 cases have been previously reported. We report two cases of rhabdoid colorectal carcinoma, one arising in the sigmoid colon of a 62-year-old man and another in the rectum of an 83-year-old woman. In both cases, the patients had advanced tumors with lymph node metastases. The tumors mostly showed a diffuse arrangement with rhabdoid feature...