The association of secreted frizzled related protein type 4 (Sfrp4) as an antagonist of Wnt mole-cules in apoptotic events has been reported previously. Moreover, its increased expression has been reported in the ovary of women with polycystic ovary (PCO). We have demonstrated in-creased Sfrp4 in PCO-induced rat ovary related to an increased number of apoptotic follicles showing nuclear ?cateni...

A 61-year-old postmenopausal female with a past medical history of type 2 diabetes, nephrolithiasis, and recurrent urinary tract infections presented to an outpatient urology clinic chief complaint frequency, urgency, burning after micturition. Associated symptoms included nausea, low-grade fever chills, right flank pain. After treatment antibiotics did not relieve all her symptoms, imaging was...

The purpose of this study was to explore the use of a commercial thermal printer to deposit Chinese Hamster Ovary (CHO) and embryonic motoneuron cells into pre-defined patterns. These experiments were undertaken to verify the biocompatibility of thermal inkjet printing of mammalian cells and the ability to assemble them into viable constructs. Using a modified Hewlett Packard (HP) 550C computer...

The respiratory tract contains numerous peptides secreted from special pulmonary epithelial cells whichare called endocrine cells. The function of neuroendocrine cells is modulated by amines. Serotonin has strong vasomotor and bronchomotor effects in the airway mucosa. The objective of this study was to determine presence and distribution of serotonin-positive endocrine cells in respiratory tra...

ovary undergoes several changes after the menopause. The main characteristics of the post-menopausal ovary are a loss of follicles and several changes as a consequence of apoptotic processes. Signs of atrophy and fibrosis are evident. Primordial follicles are usually absent in postmenopause, whereas corpora atretica, hemorrhagica and albicantia, scar tissue, and simple follicular cysts are comm...

Reactive oxygen species produce oxidized bases, deoxyribose lesions and DNA strand breaks in mammalian cells. Previously, we demonstrated that aldehydic DNA lesions (ADLs) were induced in mammalian cells by 10 mM hydrogen peroxide (H2O2). Interestingly, a bimodal H2O2 dose-response relationship in cell toxicity has been reported for Escherichia coli deficient in DNA repair as well as Chinese ha...