Mothers with obesity or gestational diabetes mellitus have low circulating levels of adiponectin (ADN) and frequently deliver large babies with increased fat mass, who are susceptible to perinatal complications and to development of metabolic syndrome later in life. It is currently unknown if the inverse correlation between maternal ADN and fetal growth reflects a cause-and-effect relationship....

Newborn weight exceeding 4000 g or 4500 is considered as macrosomia, incidence of which varies from 6 to 10% all deliveries. Maternal diabetes, obesity, age >35 years, male baby, history previous multiparity are few risk factors. It associated with several maternal and neonatal complications presents an obstetric challenge there no consensus regarding the most appropriate route delivery for ...

BACKGROUND To identify risk factors, beyond fetal weight, associated with adverse maternal outcomes in delivering infants with a birthweight of 4000 g or greater, and to quantify their role in maternal complications. METHODS All women (n = 1564) with singleton pregnancies who attempted vaginal delivery and delivered infants weighing at least 4000 g, in two French tertiary care centers from 20...

background: free fetal dna (ffd) in maternal plasma/serum has increasingly become the source of fetal material for diagnostic purposes in recent years. this source of fetal material can be used for sex determination. rh typing paternally inherited sequences and compound heterozygosity. reports on the lack of consistent pcr amplification of y-chromosome sequences of ffd in maternal plasma/serum ...

Introduction: Pregnancy induced hypertension is one of the most common causes of both maternal and fetal morbidity and mortality. This study aims to determine the feto-maternal outcome and correlation with severity of PIH. Material and methods: 250 cases of PIH were studied and divided according to severity. The maternal and fetal outcome parameters were documented and analysed using statistica...

Placental chorioangioma is the most common benign non-trophoblastic tumor of the placenta. It is derived from primitive chorionic mesenchyme and is typically vascular accounting for approximately 1 % of all pregnancy [1]. Chorioangioma is the most common histological type of placental tumor. An increased incidence rate of chorioangioma is associated with maternal age, hypertension, diabetes, fe...

Circulating nucleic acids are present in small amounts in the plasma of healthy individuals. However the discovery of circulating nucleic acids has long been explored for the noninvasive diagnosis of a variety of clinical conditions. The first studies concerning the detection of circulating DNA were investigated for finding various forms of cancer. Metastasis and recurrence in certain tumour ty...

Circulating nucleic acids are present in small amounts in the plasma of healthy individuals. However the discovery of circulating nucleic acids has long been explored for the noninvasive diagnosis of a variety of clinical conditions. The first studies concerning the detection of circulating DNA were investigated for finding various forms of cancer. Metastasis and recurrence in certain tumour ty...

Despite the dramatic decline in maternal and perinatal morbidity and mortality over the past few decades, controversy still exists regarding the care of pregnant women with both pregestational and gestational diabetes mellitus. Carbohydrate intolerance is the most common metabolic complication of pregnancy. A review of the literature over the last two decades indicates that the incidence of ges...