MOTIVATION Efficient, accurate and automatic clustering of large protein sequence datasets, such as complete proteomes, into families, according to sequence similarity. Detection and correction of false positive and negative relationships with subsequent detection and resolution of multi-domain proteins. RESULTS A new algorithm for the automatic clustering of protein sequence datasets has bee...

Abstract. We show that in the large matrix limit, the eigenvalues of the normal matrix model for matrices with spectrum inside a compact domain with a special class of potentials homogeneously fill the interior of a polynomial curve uniquely defined by the area of its interior domain and its exterior harmonic moments which are all given as parameters of the potential. Then we consider the ortho...

This paper presents two methods based on domain decomposition concepts for determining the diagonal of the inverse of a sparse matrix. The first uses a divide-and-conquer principle and the ShermanMorrison-Woodbury formula, and assumes that the matrix can be decomposed into a 2 × 2 block-diagonal matrix and a low-rank matrix. The second method is a standard domain decomposition approach in which...

this paper explains a model for analyzing and measuring the propagation of order amplifications (i.e. bullwhip effect) for a single-product supply network topology considering exogenous uncertainty and linear and time-invariant inventory management policies for network entities. the stream of orders placed by each entity of the network is characterized assuming customer demand is ergodic. in fa...

background and aims: the ectodomain of matrix protein of influenza virus is a weak immunogen that is highly conserved among all subtypes of influenza a virus. tandem repeats of these genes along with linker were used to enhance immunogenicity of m2e protein and so it can be served as a universal vaccine in both humans and livestock. materials and methods: in this study, the sequences of extra-d...