The energy spectrum of the Neutron Radiation Effects Program (NREP) beam line, Target-ModeratorReflector-1 (TMR-1), at Indiana University has not been previously characterized. The facility has a unique proton source with variable pulse length (15-600 s) and energy (13 MeV). Thus, it can produce a unique and tailored neutron beam when incident on a beryllium target. Through a combination of MCN...

The authors have noticed that Figure 4C was published incorrectly in the original version of this Article. The correct Figure 4C appears below in Figure 1.

BACKGROUND Dosimetric characteristics of a high dose rate (HDR) GZP6 Co-60 brachytherapy source have been evaluated following American Association of Physicists in MedicineTask Group 43U1 (AAPM TG-43U1) recommendations for their clinical applications. MATERIALS AND METHODS MCNP-4C and MCNPX Monte Carlo codes were utilized to calculate dose rate constant, two dimensional (2D) dose distribution...

The relationships between ocular dominance columns and intrinsic cortical circuitry were examined in brain slices prepared from the striate cortex of macaques. Ocular dominance columns in layer 4C beta were visualized in vitro following anterograde transport of rhodamine injected into the lateral geniculate nucleus in vivo. The axonal and dendritic arborizations of individual layer 4C beta cell...

"4C-amodiaquin and "4C-chloroquine were used to study drug binding by preparations of owl monkey erythrocytes infected either with a chloroquine-susceptible (CS) or with a chloroquine-resistant (CR) strain of P. falciparum. Both of these drugs are derivatives of 4-aminoquinoline, but they differ in their side chains, and there are differences in the way they are handled by preparations of eryth...

Neurons in layer 4C in macaque striate cortex show an increase in receptive field size and achromatic contrast sensitivity from the bottom to the top of the layer. Using a computational model which is based on realistic anatomical and physiological data we demonstrate that part of the observed changes can arise from differences in the overall balance between recurrent excitation and lateral inh...

Cell cycle progression of G2 fractions (75-80% G2 (4C) cells) from 8 h anaerobically cultured asynchronous hyperdiploid Ehrlich ascites tumor cells strain Karzel, separated by centrifugal elutriation, was studied after reaeration by flow cytometric methods, including the BrdU-H33258 technique and dual parameter measurements. Analyses of the growth kinetics demonstrated that one fraction of the ...

This article describes the use of four-component instructional design (4C/ID), a model to plan educational interventions for complex learning. This model was used to design a continuing education course on communication skills for health professionals in a context that is hierarchical and communal. The authors describe the 4C/ID model and provide an example of its application in designing the c...

A new class of N-(1-thia-4-azaspiro[4.5]decan-4-yl)carboxamide inhibitors of influenza virus hemagglutinin (HA)-mediated membrane fusion that has a narrow and defined structure-activity relationship was identified. In Madin-Darby canine kidney (MDCK) cells infected with different strains of human influenza virus A/H3N2, the lead compound, 4c, displayed a 50% effective concentration of 3 to 23 m...