Dans cet article, nous présentons MDDR, un nouvel algorithme de révision de contraintes définies sous forme de diagramme de décision multi-valué (MDD). En réalisant des copies partielles à la volée des MDD modifiés au cours de la recherche, MDDR parvient à une meilleure incrémentalité que MDDC proposé par Cheng & Yap en 2010 [2]. La meilleure incrémentalité, couplée à la nouvelle possibilité d’...

BACKGROUND This report investigates the longitudinal association of changes in major depressive disorder (MDD) and borderline personality disorder. METHOD A DSM-IV-diagnosed sample of 161 patients with borderline personality disorder who have been followed with repeated measures at 6, 12, 24, and 36 months are investigated to see whether those with co-occurring MDD differ at baseline and in t...

Objective Our previous studies found that disturbances in gut microbiota might have a causative role in the onset of major depressive disorder (MDD). The aim of this study was to investigate whether there were sex differences in gut microbiota in patients with MDD. Patients and methods First-episode drug-naïve MDD patients and healthy controls were included. 16S rRNA gene sequences extracted ...

BACKGROUND Facial emotion perception (FEP) is a critical human skill for successful social interaction, and a substantial body of literature suggests that explicit FEP is disrupted in major depressive disorder (MDD). Prior research suggests that weakness in FEP may be an important phenomenon underlying patterns of emotion-processing challenges in MDD and the disproportionate frequency of MDD in...

BACKGROUND Limited information exists regarding the long-term development of comorbidity between Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD; abuse/dependence). Using a representative prospective study, we examine multiple aspects pertaining to MDD+AUD comorbidity, with a focus on the relation between disorders across periods (adolescence, early adulthood, adulthood) and cumul...

BACKGROUND Research on gene × environment interaction in major depressive disorder (MDD) has thus far primarily focused on candidate genes, although genetic effects are known to be polygenic. AIMS To test whether the effect of polygenic risk scores on MDD is moderated by childhood trauma. METHOD The study sample consisted of 1645 participants with a DSM-IV diagnosis of MDD and 340 screened ...

Introduction and objective: Migraine and major depressive disorder (MDD) frequently co-occur, but it is unclear whether depression is associated with a specific subtype of migraine. The objective of this study was to investigate whether migraine is qualitatively different in MDD patients (N1⁄4 1816) and non-depressed controls (N1⁄4 3428). Methods: Migraine symptom data were analyzed using multi...

This study examined cortisol reactivity to repeated psychosocial stressors in 35 adolescents and young adults aged 12 to 26 years. Participants were divided into three study groups: controls with no history of major depressive disorder (MDD) or childhood maltreatment (n = 18); a diagnosis of MDD at Time 1 but no history of maltreatment (MDD-only; n = 10); and both MDD and maltreatment (MDD+MALT...

BACKGROUND Convergent studies provide support for abnormalities in the structure and functioning of the prefrontal cortex (PFC) and the amygdala, the key components of the neural system that subserves emotional processing in major depressive disorder (MDD). We used resting-state functional magnetic resonance imaging (fMRI) to examine potential amygdala-PFC functional connectivity abnormalities ...

objective: thought-action fusion (taf) refers to the tendency to assume incorrect causal relationship between one’s own thoughts and external reality, in which, thoughts and actions are treated as equivalents. this construct is present to development and maintenance of many psychological disorders. the aim of the present study was to predict obsessive-compulsive disorder (ocd) and its types, an...