The features of fibrocystic disease of the pancreas are well recognized following the description by Andersen in 1938 of three main clinical forms. The first is that of intestinal obstruction in the first few days of life due to meconium ileus. About a fifth of all cases present with failure to pass meconium which is followed by vomiting and abdominal distension. It results from inspissation of...

Introduction The history of the word ‘ meconium' holds interest for all of us involved in perinatal care. Meconium is the dark greenish brown material excreted in utero, usually from a full term fetus. Fetal hypoxic distress causes neural stimulation of the mature gastrointestinal tract, which is caused by vagal stimulation from head or cord compression; resulting in peristalsis of the gut and ...

The decrease in the incidence of MAS in the period of a decade has been attributed to the reduction in post-term delivery, aggressive management of abnormal heart rate monitoring, and decreased number of infants with a low Apgar score. [4]Elective induction of labour for pregnancies at or beyond 41 weeks has been shown to be associated with significant reduction in the incidence of MAS and fewe...

INTRODUCTION Giant cystic meconium peritonitis is relatively rare. Patients often present with nonspecific physical findings such as distension and emesis. Plain abdominal films remain invaluable for identifying the characteristic calcifications seen with a meconium pseudocyst, and large eggshell calcifications are pathognomonic for the giant cystic subtype. CASE PRESENTATION We present class...

Aim: The purpose of this study was to assess whether the intrapartum amnioinfusion (AI) in the presence of meconium-stained amniotic fluid (MSAF) influence the rate of cesarean section and perinatal outcome. Material and methods: The investigated group consisted of 405 pregnant women in labor with meconium-stained amniotic fluid: 163 had performed AI, and 242 constituted a control group (withou...

High blood trypsin levels during early days of life are found in newborns subsequently diagnosed to be affected by cystic fibrosis. The authors compared the validity of the traditional meconium test with the blood immunoreactive trypsin (IRT) assay, carried out in parallel on 113,302 neonates from three regions of North-eastern Italy. The meconium test showed a sensitivity of 57.7%. The sensiti...

OBJECTIVE The cause of meconium stained amniotic fluid in term healthy pregnancies is not clearly understood yet. The aim of this study was to investigate the placental ultrastructural changes and placental apoptosis in pregnancies complicated with meconium stained amniotic fluid. MATERIAL AND METHOD The study group was composed of mothers (n: 13) and their term, appropriate for gestational a...

We report a case of ileal atresia with meconium peritonitis evaluated by fetal MRI. Prenatal ultrasounds in the third trimester initially demonstrated a cystic abdominal mass that resolved with development of dilated bowel loops. Fetal MRI at 32 weeks gestation identified a perihepatic collection with several dilated small bowel loops and normal sized meconium filled rectosigmoid consistent wit...

Meconium peritonitis is defined as aseptic chemical inflammation caused by an intrauterine bowel perforation. Its incidence 1 in 35,000 live births. We present a case of meconium presented at second day postnatal life with isolated gross fetal ascites. Exploratory laprotomy was performed, suggestive ascites fecal contamination and perforation terminal ileum for which ileal resection double barr...