AIM To question the observer reliability or agreement of reports on the intranodal and extranodal tumour growth patterns in early metastasised non-small cell lung cancer (NSCLC). METHODS In a pilot study original histological sections of mediastinal lymph node metastases from NSCLC obtained by lymph node dissection (n = 82) or by mediastinoscopy (n = 62) were examined and classified independe...

Forty-four patients coming to surgery for carcinoma of the bronchus underwent preoperative staging of the mediastinum by computed tomography (CT scanning) and surgical exploration of the mediastinum by cervical mediastinoscopy or left anterior mediastinotomy or both. Where mediastinal nodes were affected the sensitivity and specificity of computed tomography was inferior to that of mediastinosc...

A 42-year-old male presented with an 8-month history of a thymic tumor associated with myasthenia gravis (MG) (Figure 1). The clinical stage was IIa according to the Myasthenia Gravis Foundation of America (MGFA), an electromyography (EMG) study was abnormal, and serum acetylcholine receptor (AChR) antibody testing was positive. The patient’s clinical state was stable on pyridostigmine bromide,...

Mature teratoma is a common anterior mediastinal tumour. However, occurrence of transformed malignant component within it is very rare. We report a case of a 32-year-old female presenting with dry cough and chest pain. Contrast-enhanced computed tomography (CT) showed a large thin-walled cystic lesion measuring 11.4 cm x 10.6 cm x 10.0 cm in the anterior mediastinum. Right postero-lateral thora...

Intrathoracic desmoid tumours are rare soft-tissue neoplasms arising from fascial or musculo-aponeurotic structures, accounting for less than 0.03% of all neoplasms. Most cases in fact represent intrathoracic extension of chest wall tumours. This case report describes the largest recorded true intrathoracic desmoid tumour without mediastinal or chest wall invasion. The tumour was completely exc...

Thymoma is the commonest mediastinal tumour but a rare type of thymic unknown aetiology. The overall incidence thymoma 0.13 per 100,000 persons year which even rarer in pregnancy. Until this date, specific link between and pregnancy has not been identified. Presentations are also variables includes chest pain, respiratory insufficiency, superior vena cava syndrome or non-specific symptoms like ...