Introduction: Health tourism refers to travel for the use of services that improve or promote the physical or psychological health of an individual in a location apart from their place of residence lasting over 24 hours. Health tourism provides a sizeable share of revenues derived from the health sector in some countries. The high potential for health tourism in Iran, especiall...

This volume consists of four sections: the largest is on "Statistics in Medical Research" and is a general account of the non-technical aspects of the subject; a section on "NMethods in Environmental Medical Research" makes up the second major portion of the book; and the volume is completed by two smaller sections, of some 30 to 40 pages each, on "Some Methods of Studying Human Genetics" and t...

What is it famous for? While being the main UK government's agency for funding biomedical research, it is probably best known for having nurtured British molecular biology in Cambridge in the golden decade of the 1950s — whence came the double helix model of DNA (James Watson and Francis Crick), the first amino-acid sequence of a protein (insulin, Fred Sanger), and the first three-dimensional p...

A common model for p-values from multiple hypothesis tests is the “two-groups” model[1], where the p-values are assumed to be drawn from the mixture distribution: p ∼ π0f0 + (1− π0)f1 where π0 is the proportion of p-values corresponding to tests where the null hypothesis is true, f0(·) is the density of the p-values under the null hypotheses and f1(·) is the density of p-values under the altern...

Scope of the Problem The field of transfusion medicine began 100 years ago, in 1900, with the discovery by Landsteiner of the ABO blood group system. This discovery demonstrated thatplasmaproteinshavedefined specificities.Theseplasmaproteins, later termedantibodies, recognizeepitopeson red blood cells. These discoveries constituted a starting point for blood banking—collection and storage of bl...

The challenging circumstances that confronted military caregivers during the years of war in Afghanistan and Iraq established the imperative for military-oriented medical research. The burden of injury and illness resulting from this long period of combat operations, and the unique clinical and logistical considerations it engendered provide a compelling rationale for requirement-driven, well-c...

The President: Good evening, ladies and gentlemen. We are in for another treat. Having had dinner this evening with our speaker, Dr Peter Wilmshurst, I can assure you that he is a man of many parts. He is a cardiologist at Shrewsbury and was formerly at St Thomas's. I think he has been irritated by the comments in the media about expert witnesses, because he said to me in an e-mail, " I will ju...

THE ASSOCIATION BETWEEN FATTY LIVER and sudden death has long been suspected, particularly in forensic pathology, but its pathogenic mechanisms remain elusive. This report describes several cases of fatty liverassociated sudden death in connection with extensive right ventricular fatty replacement. On the basis of the findings described in this study, it is hypothesized that extensive fatty rep...

Background: Laser-Doppler imaging (LDI) of cutaneous blood flow is beginning to be used by burn surgeons to predict the healing time of burn wounds; predicted healing time is used to determine wound treatment as either dressings or surgery. In this paper, we do a statistical analysis of the performance of the technique. Methods: We used data from a study carried out by five burn centers: LDI wa...

Chronic myeloid leukemia (CML), a hematopoietic stem cell (HSC) disorder, cannot be eradicated by conventional chemotherapy or the tyrosine kinase inhibitor (TKI) imatinib mesylate (IM). This disease persistence results from a population of quiescent CML HSC that are also not effectively targeted by the second generation BCR-ABL TKIs, dasatinib (DAS) or nilotinib in vitro. To target CML stem/pr...