Background: Outcome after transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) is highly variable. Aims: To identify factors affecting outcome after TACE forHCC. Methods: We conducted a retrospective analysis of HCC patients treated with TACE from January 2001 to December 2010 at the VA Medical Center, Gainesville, Florida using Fisher’s exact test and Mann Whitney U testfo...

Concurrent systems are notoriously difficult to program. They suffer from such problems as race conditions, deadlocks, and livelocks in addition to all the bugs encountered in sequential programs. Better methods are necessary to write correct programs for concurrent systems. In this thesis I will focus on a class of concurrent systems call ‘ensembles’. An ensemble is a massively distributed sys...

Background and Aim: Acute variceal bleeding (AVB) in patients with cirrhosis continues to have high mortality. Predicting 6-week mortality from baseline variables is essential for optimal focused management of who are at higher risk Many models been used predicting mortality, but most them lack precision require further validation. In this study, we aimed find significant predictors develop a p...

UNLABELLED The Model for End-Stage Liver Disease (MELD) or similar scoring system is proposed in the UK for prioritization for liver transplantation. We evaluated the reproducibility of creatinine measurements and therefore MELD scores in four liver transplant units in the UK. METHODS All transplant units were invited to participate; four agreed to do so, contributing 36 patients awaiting liv...

Investigations on survival of patients with hepatitis B virus related acute-on-chronic liver failure (HBV-ACLF) are sparse and urgently needed. The current study aimed to evaluate the prognostic value of circulating cell death biomarkers (M30-anigen, M65-antigen and HMGB1) for HBV ACLF. In this prospective study (2/2013-8/2014), 94 patients including 54 HBV-ACLF and 40 chronic hepatitis B (CHB)...

CONTEXT The Model for Endstage Liver Disease (MELD) score serves as the basis for the distribution of deceased-donor (DD) livers and was developed in response to "the final rule" mandate, whose stated principle is to allocate livers according to a patient's medical need, with less emphasis on keeping organs in the local procurement area. However, in selected areas of the United States, organs a...

Significant research has been dedicated to the development of creativity support tools, tools intended to amplify human creativity in the arts, sciences, and design disciplines. While examples of such tools abound, instruments are generally lacking to systematically and reliably assess these tools’ impact on the creative process. Without these instruments, it is difficult to identify what aspec...

Ice streams are a fact of ice-sheet dynamics, draining up to 90% of the ice. Thermal convection in ice below the density inversion is a speculation. An attempt is made to meld the two in such a way that the speculation becomes an explanation for the fact.

OBJECTIVE To determine the association of Model for End stage liver disease (MELD) score to the outcome of cirrhotic patients with bacterial infection and to compare it with Child-Turcott-Pugh (CTP) score. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, from January 2005 to December 2007. METHODOLOGY Patients with diagnosis of liver c...

BACKGROUND Several prognostic models have emerged in alcoholic hepatitis (AH), but lack of external validation precludes their universal use. AIM To validate the Maddrey Discriminant Function (DF); Glasgow Alcoholic Hepatitis Score (GAHS); Mayo End-stage Liver Disease (MELD); Age, Bilirubin, INR, Creatinine (ABIC); MELD-Na, UK End-stage Liver Disease (UKELD), and three scores of corticosteroi...