This work investigates the process of extraction of lemon balm (Melissa officinalis L.) by treatment with carbon dioxide at supercritical conditions. The process kinetics is studied at different operational conditions, and the influence of some important regime parameters (pressure, temperature particle size, solvent flow-rate) on the extraction yield is experimentally determined. Besides the i...

Speciation is an important evolutionary process that occurs when barriers to gene flow evolve between previously panmictic populations. Although individual barriers to gene flow have been studied extensively, we know relatively little regarding the number of barriers that isolate species or whether these barriers are polymorphic within species. Herein, we use a series of field and lab experimen...

1. Patient Engagement and the PCMH: A Pilot Survey in Four Clinical Settings Carole Upshur UMMS/DFMCH; Lee Hargraves, DFMCH; Achankeng Afiadata, Azra Borogovac, Julianna Clough, Jonathan Eisenberg, Josephine Harrington, Cailtin Lawrence, John Madore, Navine Nasser-Ghodsi, Jennifer Perez, Melissa Pergakis, Andrew Piper, Matthew Sloan, and Karen Tanner (Clinical/Translational Research Pathway stu...

OBJECTIVE Melissa officinalis (lemon balm) is contemporaneously used as a mild sedative and/or calming agent. Although recent research has demonstrated modulation of mood in keeping with these roles, no studies to date have directly investigated the effects of this herbal medication on laboratory-induced psychological stress. METHODS In this double-blind, placebo-controlled, randomized, balan...

1 Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Afyon Kocatepe University, Afyonkarahisar, TURKEY 2 Faculty of Medicine, Department of Pharmacology, Afyon Kocatepe University, Afyonkarahisar, TURKEY 3 Faculty of Veterinary Medicine, Department of Internal Medicine, Afyon Kocatepe University, Afyonkarahisar, TURKEY 4 Faculty of Art and Science, Department of Chemistr...

The end of monkey research?” ask Melissa Suran and Howard Wolinsky (2009) against a background of growing concern over the use of primates in research. Indeed, the one factor that might have the biggest impact on primate research in Europe is the revision of Directive 86/609, which will greatly affect the work of many scientists. It is therefore in the interest of all researchers to get an unbi...

Melissa officinalis L. called in popular language lemon balm is a medicinal plant belonging to the Lamiaceae family. The contains variety of bioactive compounds among which volatile oils, flavonoids and phenolic acids. These are responsible for lot beneficial effects disease relief. Lemon has antioxidant, antimicrobial, neuroprotective, anxiolytic, spasmolytic other effects. Important its antio...