A 17-year-old boy with Down's syndrome was last known normal at 11 pm and found with right-sided weakness and facial droop at 1 Am. In the local hospital, stroke was suspected and he was flown to a tertiary care center with mRI and neuro-logical expertise available 24 hours a day. On arrival, his National Institutes of Health Stroke Scale was 12. He had a right partial hemianopia, severe right ...

C holesterol management is the centerpiece of cardiovas-cular risk reduction. The most commonly used tool for cholesterol control is a daily statin, and the recent American Heart Association/American College of Cardiology guidelines have sanctified this approach by endorsing widespread use of statins in large groups of patients, including those with cardiovascular disease, hypercholesterolemia,...

Spatial data mining seeks to discover meaningful patterns from data where a key dimension of the data is geographical location. This spatial dimension becomes important when data either refer to specific locations andJor have significant spatial dependence and which needs to be taken into consideration if meaningfid patterns are to emerge. For point data there are two main groups of approaches....

Dear Editor, Diabetes is a major epidemic chronic metabolic ailment worldwide (WHO, 2008). It is characterized by insufficiency of insulin secretion and/or action, insulin resistance, and abnormal metabolism of glucose, lipid and protein (WHO, 2008; Middha et al., 2011). Today, diabetes has become a pandemic affecting approximately 5 % of people in both developed and developing countries. Globa...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Excessive calorie intake and subsequent obesity is associated with multiple chronic diseases, including type 2 diabetes melli-tus, hypertension, dyslipidemia, coronary heart disease, stroke, and some types of cancers such as colon cancer, endometrial cancer,...

H eart failure is the primary cause of adult mortality in the Western world, affecting 1% to 2% of the population, including ≤10% of people >70 1. Several disease settings, including coronary artery disease, hypertension, diabetes melli-tus, and hypertrophic cardiomyopathy, promote a maladaptive response characterized by myocyte hypertrophy and fibrosis. The latter refers to excessive extracell...

although it is impossible to exclude a slight downward assay drift of 0.1% over the 56-week study period. In conclusion, whole blood stored at Ϫ70 °C for 1 year is stable for later measurement of HbA 1c by HPLC in individuals without diabetes. This eliminates the need to analyze fresh blood in epidemiology and potentially could permit HbA 1c to be measured in existing cohorts with stored whole ...

Arterial stiffness is one of the most important determinants of increased systolic arterial pressure and pulse pressure, and is closely associated with hypertension, hyperlipidemia, type 2 diabetes melli-tus, and artery hardening (1-2). The American College Sports Medicine guideline states regular exercise can prevent and treat cardiovascular system dysfunction including arterial stiffness (3)....

When studying the increased longevity of the mentally handicapped (1) we noted a number of cases of diabetes mellitus. We therefore decided to survey the total population of the Stoke Park Group of Hospitals in Bristol resident on 1 August 1982. There were 1,116 mentally handicapped patients of whom 23 were diabetic. (Thirteen females and ten males). At the time of the diagnosis the age range w...

The Afghan resistance sees its struggle more in terms of a "holy war" (jihad) than as a war of national liberation. In a country in which reference to the "nation" is avery recent phenomenon, where the State is perceived as exterior to society and where allegiance belongs to the local community, Islam remains the sole point of reference for all Afghans. It is only in the southern Pushtun tribal...