Subdivision surfaces are a popular representation for the freeform shape in geometric modeling. While the subdivision process rapidly converges to a smooth shape, computing and rendering all the vertices is too expensive in the sense of the memory consumption and run time, and also superfluous. Our work was inspired by a demand for a rendering of dynamic scenes and an interactive rendering of t...

Problem statement: Displaced subdivision representation possesses a number of attractive features for efficient and convenient processing tasks like editing, geometry compression, animation, scalability and adaptive rendering of polygonal models. In this representation, a detailed surface model was built as a scalar-valued displacement map over a smooth domain surface. The construction of the s...

In flowering plants, mitochondrial and chloroplast mRNAs are edited by C-to-U base modification. In plant organelles, RNA editing appears to be generally a correcting mechanism that restores the proper function of the encoded product. Members of the Arabidopsis RNA editing-Interacting Protein (RIP) family have been recently shown to be essential components of the plant editing machinery. We rep...

RNA editing is vital to provide the RNA and protein complexity to regulate the gene expression. Correct RNA editing maintains the cell function and organism development. Imbalance of the RNA editing machinery may lead to diseases and cancers. Recently, RNA editing has been recognized as a target for drug discovery although few studies targeting RNA editing for disease and cancer therapy were re...

RNA editing in Trypanosoma brucei is posttranscriptional uridylate removal/addition, generally at vast numbers of pre-mRNA sites, but to date, only single editing cycles have been examined in vitro. We here demonstrate achieving sequential cycles of U deletion in vitro, with editing products confirmed by sequence analysis. Notably, the subsequent editing cycle is much more efficient and occurs ...

Conceptual design is usually done with paper and pen. Notepad computers open a new way for designing pen-based user interfaces for supporting such kind of design activities. However, pen-based user interfaces have some aws, such as the recognition rate of handwritten characters, the size of memory and display, which limits the application of such kind of computers. The main idea we have is to c...

The use of algorithms for calculation and analysis of RNA secondary structures has largely been limited to mainframe computers, mainly due to the 16-bit memory restrictions imposed by MS-DOS. The program presented here, RNAdraw, moves calculations to the 32-bit Microsoft Windows environments with an intuitive user interface with extensive viewing, editing and printing possibilities. The algorit...

In this paper we present the results from a pilot study undertaken with translation students to compare community forum content post-editing performance based on suggestions from different translation systems. Output from both Translation Memory (TM) and Statistical Machine Translation (SMT) was presented to participants in the ACCEPT online postediting environment, where they needed to perform...

Addiction is a complex and devastating disease that hijacks homeostatic reward signaling, resulting in progressive loss of control over drug consumption and aversive withdrawal symptoms following prolonged abstinence. Recent studies have suggested that epigenetic modifications, particularly DNA methylation and histone methylation, regulate the long-term storage and maintenance of memory, and th...