نتایج جستجو برای: mental accumulation
تعداد نتایج: 407603 فیلتر نتایج به سال:
Critical ethnographies and methods of relational comparison provide tools for reconfiguring area studies to challenge imperial visions of the world; for illuminating power-laden processes of constitution, connection, and disconnection; and for identifying slippages, openings, contradictions, and possibilities for alliances. Crucial to this project are Lefebvrian conceptions of the production of...
Senescence (aging) is defined as a decline in performance and fitness with advancing age. Senescence is a nearly universal feature of multicellular organisms, and understanding why it occurs is a long-standing problem in biology. Here we present a concise review of both evolutionary and mechanistic theories of aging. We describe the development of the general evolutionary theory, along with the...
Guanylic nucleotide biosynthesis is a conserved and highly regulated process. Drugs reducing GMP synthesis affect the immunological response and mutations enabling guanylic-derivative recycling lead to severe mental retardation. While the effects of decreased GMP synthesis have been well documented, the consequences of GMP overproduction in eukaryotes are poorly understood. In this work, we sel...
Mitochondrial dysfunction and altered proteostasis are central features of neurodegenerative diseases. The pitrilysin metallopeptidase 1 (PITRM1) is a mitochondrial matrix enzyme, which digests oligopeptides, including the mitochondrial targeting sequences that are cleaved from proteins imported across the inner mitochondrial membrane and the mitochondrial fraction of amyloid beta (Aβ). We iden...
Theory suggests that the risk of extinction by mutation accumulation can be comparable to that by environmental stochasticity for an isolated population smaller than a few thousand individuals. Here we show that metapopulation structure, habitat loss or fragmentation, and environmental stochasticity can be expected to greatly accelerate the accumulation of mildly deleterious mutations, lowering...
The corruption is a secondary phenomenon, because there are economic preconditions causing it. Unless the achievement of macroeconomic stability and the formation of the institutions appropriate to a market economy reach their logical ending, both of them may become the cause of corruption in the post-Communist transformation of the economy. In order to restrict corruption and establish the ins...
Soil biofilters and related systems based onthe use of natural filter beds have been usedfor several years for solving specific airpollution problems. Over the past decade,significant improvements have been brought tothese original bioprocesses, among which thedevelopment and use of new inert packingmaterials. The present paper overviews the mostcommon inert packings used in biofiltration ofwas...
This paper presents an algorithm for computing algebraically relative resolvents which enhances an existing algorithm by avoiding the accumulation of superfluous powers in the intermediate computations. The superfluous power generated at each step is predetermined over a certain quotient ring. As a byproduct, an efficient algorithm for extracting an n-th root of a univariate polynomial is obtai...
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