Several epidemiological studies have shown that exercise (EX) and physical activity (PA) can prevent or delay the onset of different mental disorders, and have therapeutic benefits when used as sole or adjunct treatment in mental disorders. This review summarizes studies that used EX interventions in patients with anxiety, affective, eating, and substance use disorders, as well as schizophrenia...

A system-level model of spatial working memory is described, using the author’s computer science and logical modeling approach. The remembered mental image is located in a lateral parietal module, and plans are executed and sequenced in a dorsal prefrontal module. Mental images are saved and maintained by explicit messages from the currently executed plan and can be reinstated for use in motor ...

A study led by a scientist at the School of Medicine shows that hormone therapy has a negligible effect on verbal memory and other mental skills regardless of how soon after menopause a woman begins therapy. The study is the first large, long-term clinical trial to compare the effects of estradiol, a type of estrogen, on the mental capabilities of women who commence treatment soon after menopau...

INTRODUCTION AND OBJECTIVES Motor and cognitive development of children with Down syndrome (DS) is delayed and inharmonic. Neuro-muscular abnormalities, such as hypotonia, retained primary reflexes, and slow performance of volitional reaction, result in difficulties with body balance. The aim of the presented study is to assess the global motor functions and body balance of children with DS in ...

This is a case report of a patient with idiopathic gingival hyperplasia and an undiagnosed genetic disorder that demonstrated static encephalopathy, mental retardation, developmental delay, seizures, hypotonia, and severe gingival hypertrophy. The clinical dental management and attempts to obtain a genetic diagnosis are described.

Environmental enrichment is used to enhance mental stimulation and physical activity and has been shown to delay onset and progression of a range of brain disorders. Now, Cao et al. (2010) report in Cell that this paradigm also exerts strong influences beyond the brain and is capable of suppressing tumor growth in mice.

The authors measured coenzyme Q10 (CoQ10) concentration in muscle biopsies from 135 patients with genetically undefined cerebellar ataxia. Thirteen patients with childhood-onset ataxia and cerebellar atrophy had markedly decreased levels of CoQ10. Associated symptoms included seizures, developmental delay, mental retardation, and pyramidal signs. These findings confirm the existence of an ataxi...

This paper verifies the effect of delay of voice information between the participants in a conference telephone call on the subjective assessment of the quality of the conversation. And evaluate changes in the assessment of individual respondents based on their mental state. Criterion of transmission quality is a parametr MOS obtained from respondents of subjective tests before and after the st...

The authors describe a 6-year-old girl with developmental delay, psychomotor regression, seizures, mental retardation, and autistic features associated with low CSF levels of 5-methyltetrahydrofolate, the biologically active form of folates in CSF and blood. Folate and B12 levels were normal in peripheral tissues, suggesting cerebral folate deficiency. Treatment with folinic acid corrected CSF ...