QT prolongation is a serious adverse drug effect, which is associated with an increased risk of Torsade de pointes and sudden death. Many drugs, including both cardiac and non-cardiac drugs, have been reported to cause prolongation of QT interval. Although meperidine has not been considered proarrhythmic, we present a unique case of a 16-year-old boy without an underlying cardiac disease, who d...

conclusions the results of this study showed that ketamine and pethidine are both equally effective in the reduction of postoperative shivering. results there was no statistically significant difference between the shivering intensity in both groups. only regarding the shivering in the first minute after entering the recovery room, there was an obvious difference between ketamine and pethidine ...

We present a case of "inverted Tako-Tsubo" syndrome in a woman sedated with meperidine before undergoing a colonscopy. We discuss possible etiology of this ventricular dysfunction.

Background: Clinical investigations have reported several anesthetic properties of intrathecal injections of meperidine. The purpose of this study was to investigate the effect of adding meperidine to intrathecal heavy lidocaine on hemodynamic changes and blood loss in patients undergoing elective suprapubic open prostatectomy. Methods: In a randomized double-blind clinical trial, 77 pa...

conclusions totally, according to the obtained results it may be concluded that paracetamol and diclofenac combination would have a better efficacy in postoperative pain control and need reduction to additive analgesia compared to meperidine. patients and methods one hundred and twenty women candidates for elective cesarean section under spinal anesthesia categorized as asa class i were selecte...

Introduction: Meperidine has the advantages of being widely available and inexpensive. It would be highly cost-benefit if it is used at doses that are without any side-effect. Thus, this study aimed to assess the effect of meperidine 5 mg as an additive to bupivacaine for spinal anesthesia on postoperative pain in cesarean section surgery. Methods: This double-blind randomized clinical trial w...

BACKGROUND Anterior shoulder dislocation is one of the most common complaints of patients referred to emergency departments. Intravenous opiates and benzodiazepines are traditionally prescribed in order to relieve the pain in this group of patients; however, complications always pose a problem. OBJECTIVE To compare the pain relief and complications following intra-articular lidocaine and intr...

conclusions addition of meperidine or fentanyl to lidocaine and epinephrine solution increases the duration of postoperative analgesia in cesarean section. meperidine is a recommended adjuvant according to longer duration of analgesia and lower complications. results the mean duration of analgesia with meperidine, fentanyl or placebo were 9.46 ± 0.6, 6.27 ± 0.45, 2.06 ± 0.13 hours, respectively...

The myocardial kinetics of meperidine and the relationship between these kinetics and the effect of meperidine on myocardial contractility (maximum positive rate of change of left ventricular pressure) were examined by analysis of previously published data collected in sheep after the i.v. injection of 100 mg of meperidine over 1 s. There was significant hysteresis between reductions in myocard...

Aim Percutaneous needle liver biopsy (PLB) is frequently associated with pain and anxiety. This may discourage the patients for biopsy, and rebiopsies, if needed. We planned a study to investigate the efficacy of additional analgesia or sedation for PLB. Materials and methods The study has been designed as a single-center, prospective study. The PLB was planned for 18- to 65-year-old consecut...