A 29-year-old gardener developed acute renal failure following the ingestion of 'Mersil', a combination of mercurous and mercuric chloride, achieving a plasma mercury concentration of 22,000 nmol/litre (400 micrograms/litre). Haemodialysis and charcoal haemoperfusion were ineffective in removing mercury despite prior treatment with the chelating agent dimercaprol. The acute renal failure resolv...

Plasma Enzyme Activities in Coturnix Quail Fed Graded Doses of DDE, Polychlorinated Biphenyl, Malathion and Mercuric Chloride. DIETER, M. P. (1974). Toxicol. Appl. Pharmacol. 27, 86-98. Male Coturnix quail (Coturnix coturnixjaponica) were fed diets for 12 weeks containing graded levels of DDE, polychlorinated biphenyl (Aroclor 1254), malathion, and mercuric chloride. Birds were bled prior to ex...

The effects of substrates and inhibitors on the conformation of yeast cytoplasmic pyruvate decarboxylase (Z-oxo-acid carboxy-lyase, EC 4 .l .l .l) has been examined using the technique of automated tritium-hydrogen exchange. This experimental approach, as used in this study, reflects primarily the number of solvent-inaccessible or “core” hydrogens in the protein. Yeast cytoplasmic pyruvate deca...

1. A method is described for the estimation of thiol ester groups. The thiol ester is converted into the corresponding thiol by reaction with ammonia; the thiol is then titrated amperometrically with mercuric chloride. 2. The method may be used in the presence of SH and S.S groups. The SH groups are titrated at pH3 in the presence of excess of chloride; under these conditions thiol esters do no...

Bioactive peptides such as bradykinin potentiating factor (BPF), have, anti-oxidative, anti-inflammatory, immunomodulatory and ameliorative effects in chronic diseases and play a potential role in cancer prevention. It is known that the liver and kidney accumulate inorganic mercury upon exposure, which often leads to mercury intoxication in these organs. In this study, we investigated the effec...

A method is presented for the rapid determination of total mercury in blood. The reagent used is alkaline sodium borohydride, and no digestion of the sample is needed. The detection limit and sensitivity are 1.15 and 1.59 ng of Hg, respectively. The method gives reproducible results (the CV ranged from 5.3 to 6.7% for low and high mercury blood samples, respectively), comparable to those obtain...