BACKGROUND AND PURPOSE We sought to compare the accuracy of a volumetric fully automated computer assessment of hippocampal volume asymmetry versus neuroradiologists' interpretations of the temporal lobes for mesial temporal sclerosis. Detecting mesial temporal sclerosis (MTS) is important for the evaluation of patients with temporal lobe epilepsy as it often guides surgical intervention. One f...

conclusions the psychotic symptoms due to temporal lobe epilepsy can be resolved with lamotrigine administration. introduction visual illusions and hallucinations may accompany a wide variety of disorders with many various etiologies; therefore, they are nonspecific phenomena. in a partial seizure, a localized hyper synchronous neuronal discharge evolving into a partial seizure affecting a part...

epilepsy is one of the most common neuroinflammatory disorders that affect more than 50 million people worldwide. excessive electrical discharges in neurons following neural cell damage or loss leads to recurrent seizures, which are described as epilepsy. one of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (tle), which results from hippocampal sclerosis. cu...

PURPOSE To study the relationship between the MR findings and the clinical features in temporal lobe epilepsy in childhood (less than 10 years of age). METHODS MR studies were performed with a 1.5-T imager on 38 temporal lobe epilepsy patients receiving drug therapy at the psychiatric department. These patients were divided into two groups according to their age at onset (10 years or less, 11...

OBJECTIVES The phenomenon of interictal regional slow activity (IRSA) in temporal lobe epilepsy and its relation with cerebral glucose metabolism, clinical data, MRI, and histopathological findings was studied. METHODS Interictal 18F-fluorodeoxyglucose positron emission tomography (FDG PET) was performed under continuous scalp EEG monitoring in 28 patients with temporal lobe epilepsy not asso...

background epilepsy, a well-known mostly idiopathic neurologic disorder, has to be correctly diagnosed and properly treated. up to now, several diagnostic approaches have been processed to determine the epileptic focus. objectives the aim of this study was to discover whether proton-mr-spectroscopic imaging (mrsi) aids in the diagnosis of temporal lobe epilepsy in conjunction with classical ele...

introduction: transforming growth factor-beta 1 (tgf-β1) is a pleiotropic cytokine with potent anti-inflammatory property, which has been considered as an essential risk factor in the inflammatory process of ischemic stroke (is), by involving in the pathophysiological progression of hypertension, atherosclerosis, and lipid metabolisms. -509c/t tgf-β1 gene polymorphism has been found to be assoc...

Objectives—To assess patterns of postictal cerebral blood flow in the mesial temporal lobe by coregistration of postictal TcHMPAO SPECT with MRI in patients with confirmed mesial temporal lobe epilepsy. Methods—Ten postictal and interictal Tc-HMPAO SPECT scans were coregistered with MRI in 10 patients with confirmed mesial temporal lobe epilepsy. Volumetric tracings of the hippocampus and amygd...