Background Many elements such as immunosuppressive, chemotactic and anti-inflammatory peptide that could effect on human and animals physiologic system were determined in venom. This study evaluated the use of Mesobuthus eupeus scorpion venom fractions as an immunomodulator. Methods The venom fractions collected from Khuzestan Province in South West of Iran were purified by ion exchange chrom...

The present study was undertaken to isolate 5-hydroxytryptamine (5-HT) from crude Indian red scorpion (Mesobuthus tamulus; MBT) venom as it has not been reported yet. Therefore, with the help of bioassay (using gastric fundus contractions) and fluorimetric assay methods, the 5-HT content of crude MBT venom (CV) was determined. The concentration of 5-HT in CV by either of the methods was differe...

Abstract. Shahi M, Jaberhashemi SA, Hanafi-Bojd AA, Akbari Rafinejad J. 2021. Faunistic study on scorpions and their health impact in Bashagard County, Hormozgan Province, Southern Iran. Nusantara Bioscience 13: 85-90. Scorpion sting is a major public problem tropical subtropical countries, endangering thousands of lives annually. About 2300 scorpion cases including several deaths are reported ...

  Introduction: Iranian scorpion species are classified in Buthidae and Scorpionidae with 16 genera and 25 species. In Iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming. Mesobuthus eupeus is the most common species in Iran. Its venom contains several toxin fractions which can affect the ion...

BACKGROUND Scorpion stings cause an estimated 3000 deaths per annum worldwide. We conducted a systematic review of all controlled clinical trials related to scorpion sting management. METHODS We searched PubMed, EMBASE, Scopus, Web of Science and CINAHL and included controlled prospective clinical trials (randomized or non-randomized). The following interventions were assessed: adults and chi...

In the neurotomised animals, venom-induced mean arterial pressure (MAP) and respiratory rate (RR) changes were markedly attenuated but not the heart rate (HR) changes indicating the existence of additional afferent pathway. Hence, further sets of experiments were performed to explore the afferents. Albino rats were anaesthetised with an intra-peritoneal injection of urethane (1.5 g/kg). Tracheo...

Spider venoms are complex cocktails rich in peptides, proteins and organic molecules that collectively act to immobilize prey. Venoms of the primitive hunting spider, Plectreurys tristis, have numerous neurotoxic peptides called "plectoxins" (PLTX), a unique acylpolyamine called bis(agmatine)oxalamide, and larger unidentified protein components. These spiders also have unconventional multi-lobe...

This study aimed to evaluate the clinical, histopathological and hematological effects of Mesobuthus eupeus venom on chicken organs. Adult chickens were subcutaneously injected with five doses of M. eupeus venom (0.5, 2, 5, 10 and 20 mg/kg; four chickens per each dose). Symptoms were recorded during the experiment and blood samples were collected for hematological analysis. Moreover, a complete...