نتایج جستجو برای: metabolic inhibitors

تعداد نتایج: 400066  

Journal: :Biochimica Et Biophysica Acta: Molecular Basis Of Disease 2021

To adapt to tumoral environment conditions or even escape chemotherapy, cells rapidly reprogram their metabolism handle adversities and survive. Given the rapid rise of studies uncovering novel insights therapeutic opportunities based on role mitochondria in tumor metabolic programing therapeutics, this review summarizes most significant developments field. Taking mind key carcinogenesis progre...

2015
Anne Delcher Sylvie Hily Anne Sophie Boureau Guillaume Chapelet Gilles Berrut Laure de Decker John Green

OBJECTIVES To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients. DESIGN Multicenter prospective study. SETTING Acute geriatric medicine at the University Hospital of Nantes and the Hospital of Saint-Nazaire. PARTICIPANTS Older patients aged 75 and over hospitalized in acute geriatric medicine. MEASU...

Journal: :American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 2009

Journal: :Journal of Immunology 2023

Abstract Pancreatic ductal adenocarcinoma is a malignant carcinoma with 5-year survival rate of 11% characterized poor prognosis, rising incidence, and resistance to chemo- immune-therapies. Cancer cell evasion suppression anti-tumor immune responses in pancreas cancer are regulated part by metabolic reprogramming within tumor accessory cells. We sought determine if targeted inhibition mitochon...

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