نتایج جستجو برای: metalloproteinase

تعداد نتایج: 20510  

Mashayekhi, Sohail, Saberi, Alia, Salehi, Zivar,

Background: Meningioma is one of the most common tumors of the central nervous system. It was shown that meningioma had up-regulated expression of Matrix Metalloproteinases (MMPs) that involved in cell growth, angiogenesis and metastasis.  Objectives: The aim of the study was the assessment of serum MMP-2 and -9 levels in patients with different grades of meningioma.  Materials & Me...

Journal: :Cancer research 1994
C Agarwal J R Hembree E A Rorke R L Eckert

Collagenase levels are regulated in a cell type-specific manner by a variety of growth factors and cytokines, and increased type IV collagenase activity in tumor cells has been linked to metastatic growth. In this study we compare the effects of epidermal growth factor (EGF) and transforming growth factor beta 1 (TGF beta 1) on gelatinase production in cervical epithelial cell lines. EGF is a s...

2014
Saeed Soleyman-Jahi Saharnaz Nedjat Afshin Abdirad Niloofar Hoorshad Reza Heidari Kazem Zendehdel

The prognostic role of matrix metalloproteinase-7 in gastric cancer survival has been widely evaluated. However, the results are controversial. We aimed to set up a meta-analysis to reach a conclusion on the prognostic significance of metalloproteinase-7 in gastric cancer survival as well as its association with clinicopathological parameters. We searched popular databases from 1988 until Octob...

2013
Qiuhong Fang Nancy A Schulte Huijung Kim Tetsu Kobayashi Xingqi Wang Anna Miller-Larsson Elisabet Wieslander Myron L Toews Xiangde Liu Stephen I Rennard

BACKGROUND The balance between production and degradation of extracellular matrix is crucial in maintaining normal tissue structure. This study was designed to investigate the effect of budesonide on fibroblast-mediated tissue repair and remodeling. METHODS Using human fetal lung fibroblasts in a three-dimensional collagen gel culture system, we investigated the effect of budesonide (1-1000 n...

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