background and objectives: methicillin-resistant staphylococcus aureus (mrsa) is a major cause of nosocomial and community acquired infections. detection of mrsa in laboratories is very important for treatment and appropriate infection control. the aim of this study was to evaluate cefoxitin disk diffusion method for detection of mrsa and comparison of this method with other conventional method...

ESR has undertaken national surveillance of methicillin-resistant Staphylococcus aureus (MRSA) since MRSA was first identified in New Zealand in 1975. For the next decade, MRSA remained uncommon in New Zealand, with a maximum of 13 people identified with MRSA in any one year. In a 1982 national survey of antimicrobial resistance among S. aureus, just one (0.05%) of 2077 isolates included in the...

Staphylococcus aureus is an important pathogen that can cause a variety of infections, including superficial and systematic infections, in humans and animals. The persistent emergence of multidrug resistant S. aureus, particularly methicillin-resistant S. aureus, has caused dramatically economic burden and concerns in the public health due to limited options of treatment of MRSA infections. In ...

Background Antibiotic resistance in S. aureus is one of the major concerns and the rate of MRSA has dramatically increased in recent years. Clindamycin belongs to the MLS group and is used to treat skin and soft tissue infections. Resistance to clindamycin may be inducible (iMLSB) or constitutive (cMLSB) and it is present both in MRSA and MSSA. Treatment failure has been reported both in iMLSB ...

OBJECTIVES Bactericidal activity depends on antibiotic-bacteria couples, resistance phenotype and theoretically on protein binding. This work explores the influence of protein binding on the bactericidal activity of two antibiotics, daptomycin versus vancomycin, that exhibit, respectively, different C(max) (56 versus 25.5 mg/L), protein binding (91.7% versus 36.9%) and thus theoretical free-dru...

1. Crnich CJ, Drinka P. Predicting the impact of contact precautions on methicillin-resistant Staphylococcus aureus outcomes: caution up ahead. Infect Control Hosp Epidemiol 2013;34(6):646-647 (in this issue). 2. Lee BY, Singh A, Bartsch SM, et al. The potential regional impact of contact precaution use in nursing homes to control methicillinresistant Staphylococcus aureus. Infect Control Hosp ...

OBJECTIVES This study was designed to demonstrate the characteristics of qacA/B-positive Staphylococcus aureus in China. METHODS One hundred and forty-five MRSA and 178 MSSA from clinical specimens from seven hospitals in different regions of China, 70 MRSA from superficial sites of patients and 106 MRSA from environmental samples from an ICU were collected and screened for the presence of th...

*Corresponding Author: [email protected] Abstract The aim of the study was to screening for coagulase positive methicillin resistant Staphylococcus aureus (MRSA) in healthcare workers and prevalence of nasal colonization with Staphylococcus aureus. We included 84 healthcare workers’ samples (nasal swabs) in the study. Different biochemical tests were done to isolate Staphylococcus aureus...

In this study, the use of isothermal microcalorimetry (IMC) for differentiation between methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) and MIC determination was evaluated. It was possible to differentiate between MRSA and MSSA within 4 h, whereas the standard method required 24 h. The MICs of cefoxitin were successfully determined for MRSA and MS...

Our objective was to determine the antibiotic susceptibility profiles of Staphylococcus aureus isolates recovered from 110 households of children with community-onset methicillin-resistant S. aureus (MRSA) infections. Cultures were obtained from household members, household objects, and dogs and cats, yielding 1,633 S. aureus isolates. The S. aureus isolates were heterogeneous, although more th...