background:  hydrogen has been demonstrated can selectively reduce the hydroxyl, which is the main cause of ionizing radiation-induced damage. amifostine (am) is the only radioprotective drug approved by the u.s. food and drug administration for use in radiotherapy. the purpose of the present study was to investigate the combined radio-protective effect of hydrogen rich water (hrw) and am. mate...

objective(s) sonodynamic therapy is a physical treatment which utilizes ultrasound waves with an appropriate sensitizer such as protoporphyrin ix (ppix). the activation of sensitizer depends on cavitation, and therefore, high intensity ultrasound is an important necessity. beside, high intensity ultrasound can induce side effects on the healthy tissues which have surrounded tumor. the particles...

objectives: it was aimed to investigate the effects of different doses of follicle stimulating hormone (fsh) and activin a on the growth and maturation of preantral mouse follicles during the in vitro culture. methods: preantral follicles (90-100 µm in diameter) were harvested from 6-8 week-old syrian mice and cultured in tcm199 culture medium for 6 days to see the effect of fsh and activin a. ...

objective: this study investigated the effects of adipose-derived mesenchymal stem cells (mscs) and conditioned medium injection on cell infiltration in the brains of an experimental c57bl/6 mice model of autoimmune encephalomyelitis (eae). methods: eae was induced with myelin oligodendrocyte glycoprotein (35-55 peptides) in 20 mice. mscs were obtained from the adipose tissue of c57bl/6 mice a...

Abstract Background Air pollution causes negative impacts on health. Systemic lupus erythematosus (SLE) is an autoimmune disease with diverse clinical manifestations and multifactorial etiology. Recent studies suggest that air can trigger SLE induce activity. However, this association has not been deeply investigated. Thus, the aim of study was to evaluate whether exposure fine particulate matt...

Purpose: To investigate the biological functions of miR-423-5p in a mouse model with lipopolysaccharide (LPS)-induced acute liver injury.Methods: Sixty male C57BL/6 mice were randomized into control group (n = 20), LPS 20) and + mimic 20). The levels pro-inflammatory cytokines apoptosisassociated proteins tissues determined. Finally, survival was recorded within 7 days after injection LPS.Resul...

background: using cellular phone has rapidly increased all over the world. also, the concern on the possible health hazards of electromagnetic fields (emf) induced from cell phones to reproduction has been growing in many countries. the aim of this study was to assess the consequences and effects of exposure to the cell phone radiation on the quality and survival rates of preimplantation embryo...

introduction: acoustic transient cavitation is the primary mechanism of sonochemical reaction and has potential use for tumor treatment. in this study, the in vivo anti-tumor effect of simultaneous dual-frequency ultrasound at low-level intensity (isata < 6 w/cm2) was investigated in a spontaneous murine model of breast adenocarcinoma in balb/c mice. materials and methods: forty tumor bearing m...

Background: GTS, PTSM and ATSM are bis-thiosemicarbazone ligands used in the preparation of copper radiopharmaceuticals. Chemical structure of these materials indicates that they should have radio-protective effects.Objective: To study the radio-protective effects of GTS, PTSM and ATSM. Methods: This study has focused on radio-protective effects of these compounds at different doses (20, 40 and...