The next generation of tissue engineered constructs (TECs) requires the incorporation of a controllable and optimized microstructure if they are to chemically, mechanically, and biologically mimic tissue function. In order to obtain TECs with optimized microstructures, a combination of spatiotemporally regulated mechanical and biochemical stimuli is necessary during the formation of the constru...

OBJECTIVE : The feasibility of endovascular resection of highly calcified aortic valves has already been demonstrated by our group. Different endovascular and intracardiac tractability methods were applied. In this study, these technologies were analyzed comparing the tractability, the resection time, and the lesions in the surrounding tissue. METHODS : All aortic valve resections (seven huma...

An omnidirectional mobile microrobot realized by microelectromechanical system (MEMS) actuator arrays is presented. The microrobot consists of two rigidly connected microcilia array chips, each having an 8 8 array of “motion pixels,” which are composed of four orthogonally oriented thermal bimorph actuators. This allows for reliable, accurate motion in three degrees of freedom (x;y;θ) in the pl...

Dan Reznik Stan Brown John Canny fdreznik,swb,[email protected] Dept. of EECS, UC-Berkeley, Berkeley, CA 94720 USA Abstract— We use dynamic simulation to optimize the design of an existing micro-electromechanical(MEM) device, called the Manipulation Chip (M-Chip). This device contains an excess of 10,000 moving actuators, called resonators, which oscillate torsionally at a few kHz. Parts dro...

Introduction Most implantable hearing aids currently available were developed to compensate the sensorineural hearing loss by driving middle ear structures (e.g., the ossicles). These devices are successfully used in round window (RW) stimulation clinically, although this was initially not the intended use. Here, a novel microactuator, specifically designed for RW stimulation, was tested in hum...