While the deciphering of basic sequence information on a genomic scale is yielding complete genomic sequences in ever-shorter intervals, experimental procedures for elucidating the cellular effects and consequences of the DNA-encoded information become critical for further analyses. In recent years, DNA microarray technology has emerged as a prime candidate for the performance of many such func...

In this talk I consider forward-jet production at HERA and at the Tevatron as a probe of the multiple gluon radiation induced by the BFKL evolution. To appear in the Proceedings of the International Workshop on Deep Inelastic Scattering and Related Phenomena Roma, Italy, April 1996

The recent development of complementary DNA microarray technology provides a powerful analytical tool for genetic research. This tool allows one to study expression levels in parallel which represents an enormous gain in terms of experimental time invested. But always while carrying out comparisons of expression data using measurements from a single array or multiple arrays, the question of nor...

Today’s world thrives with data and hence it is necessary to mine the available data, in order to arrive at effective knowledge patterns. Data mining is concerned with extracting knowledge from the available data and so gained knowledge is applied over the processes such as decision making, query processing, and management and so on. The DNA microarray technology enables the biologists to obser...

Motivation: Background correction is an important preprocess in cDNA microarray data analysis. A variety of methods have been used for this purpose. However, many kinds of backgrounds, especially inhomogeneous ones, cannot be estimated correctly using any of the existing methods. In this paper, we propose the use of the TV+L1 model, which minimizes the total variation (TV) of the image subject ...

background: acute promyelocytic leukemia (apl) is a unique subtype of acute leukemia. apl is a curable disease; however, drug resistance, early mortality, disease relapse and treatment-related complications remain challenges in apl patient management. one issue underlying these challenges is that the molecular mechanisms of the disease are not sufficiently understood. materials and methods: in ...

background: aflatoxin b1 (afb1) is a toxic metaboliteproduced by aspergillus species that contaminates a wide range ofagricultural products. objectives: this study was designed todevelop a rapid and highly sensitive immunoassay method inmicroarray format for quantitative detection of afb1 to evaluatethe potential of microarray platform for high-throughput screening,which can be beneficial in fo...