3,3-Dimethylcyclohexyl methyl ketone (Herbac®) is a fine fragrance compound used in the cosmetic industry. In this study, biological derivatisation of substrate 3,3-dimethylcyclohexyl by 18 fungal cultures was carried out to obtain new derivatives. Among evaluated, plant fungus Aspergillus niger ATCC 10549, biotransformed 4-hydroxy derivative 19% yield. The structure determined using NMR and GC...