See related article, pages 3145–3151. The relation between migraine and stroke has been well recognized and has been the focus of several publications.1–3 Despite many hypotheses linking the 2 disorders, the precise mechanisms are unknown, and not surprisingly very complex. In this issue of Stroke, Pezzini and colleagues4 add to this complexity by suggesting that migraine with aura may “mediate...

Although controversial, diminished activity of 5,10 methylenetetrahydrofolate reductase (MTHFR), a regulatory enzyme of homocysteine metabolism, may predispose to migraine in Turkish people. In a case-control study, we determined the prevalence of two common MTHFR polymorphisms,C677T and A1298C, in 102 migraine patients (23 migraine with aura, 70 migraine without aura and nine with tension-type...

Magnesium sulphate has been used in the acute treatment of migraines; some studies found it to be a highly effective medication in the acute control of migraine pain and associated symptoms. This randomized, double-blind, placebo-controlled study assesses the effect of magnesium sulphate on the pain and associated symptoms in patients with migraine without aura and migraine with aura. Sixty pat...

Typical migraine aura is a short-lived sensory experience coming before or during migraine and experienced by about 1/4 of all migraineurs. The experience can be visual, sensory, or result in problems with speaking or word finding. Typical visual changes are seeing spots, zigzags or crescents, flashes of light, or losing sight partially or fully, with any one of these lasting between 5 minutes ...

The evaluation and management of athletes presenting with clinical features of migraine headache with aura in the setting of sports-related head trauma is challenging. We present a case report of a 15-yr-old boy with a history of migraine with visual aura that developed acute visual disturbance and headache after a head injury during an ice hockey game. The patient underwent comprehensive asses...

About 15% of migraine patients suffer from migraine with aura. Most patients have visual or sensory symptoms. The assumed mechanism of aura in humans is a phenomenon called spreading cortical depression (1,2). Cortical spreading depression is characterized by a short cortical neuronal excitation followed by long-lasting depression. Both excitation and depression travel across the cortex at a sl...

OBJECTIVE To determine if migraineurs with aura respond differently to biofeedback/relaxation than those without aura and, if so, whether the variability in outcome can be explained by blood flow velocity. Background.-The relationship between cerebral blood flow velocity and treatment response to biofeedback/relaxation in migraine with and without aura is uncertain. METHOD Twenty migraineurs ...

Background As a complex subjective experience, pain processing may be related to functional integration among intrinsic connectivity networks of migraine patients without aura. However, few study focused on the pattern alterations in the intrinsic connectivity networks of migraine patients without aura. Results Thirty-one migraine patients without aura and 31 age- and education-matched health...

PURPOSE We present a rare case of late-onset migraine-like visual aura triggered by a large aneurysm in the left extracranial internal carotid artery. To the best of our knowledge, this is the first case of migraine-like visual aura triggered by an extracranial internal carotid artery (ICA) aneurysm. This is also the first case of migraine-like visual aura with probable thromboembolic trigger b...