It is usually held that most individuals with childhood autism have poor prognosis. According to our knowledge, a favorable outcome of a child with childhood autism is quite rare and inspires a number of controversies. A 4-year-old boy was diagnosed with childhood autism and mild mental retardation. Interviews and findings reported by other specialists were used in the diagnosis and follow-up t...

Word and nonword identification skills were examined in a sample of 80 elementary school age students with mild intellectual disabilities and mixed etiologies who were described as struggling to learn to read by their teachers. Performance on measures of receptive and expressive vocabulary, measures of phonological awareness, and measures of word and nonword identification were included for ana...

We propose a novel morphological factor estimate from structural MRI for disease state evaluation. We tested this methodology in the context of Alzheimer's disease (AD) with 349 subjects. The method consisted in (a) creating a reference MRI feature eigenspace using intensity and local volume change data from 149 healthy, young subjects; (b) projecting MRI data from 75 probable AD, 76 controls (...

BACKGROUND The transition from mild cognitive impairment (MCI) to Alzheimer's disease is characterized by a decline in cognitive performance in many domains. Cognitive performance profiles in MCI are heterogeneous, however, and additional insights into markers of incipient dementia are needed. Typically, studies focus on average or mean performance, but ignore consistency of performance across ...

Although there are many opportunities to study memory in patients with Alzheimer's disease (AD) in the laboratory, there are few opportunities to study memory for real world events in these patients. The September 11, 2001 terrorist attacks provided one such opportunity. Patients with AD, patients with mild cognitive impairment (MCI), and healthy older adults were given a telephone questionnair...

A whole method of training mildly retarded young women to thread an industrial sewing machine was compared with a pure-part and a progressive-part method. All three methods produced comparable learning, as defined by performance on the complete task one month after initial training. However, part methods were markedly superior to the whole method; fewer errors were made during trials to criteri...

With the worldwide increase in longevity and rising prevalence of cognitive disorders in the aged population, efforts have been made to characterize mild cognitive impairment (MCI) and its prevalence and/or incidence in a number of countries, given MCI may be a pre-dementia phase of degenerative conditions. The aim of this review was to retrieve the available data on the prevalence and incidenc...

Background: About 5–10% of patients with asthma suffer from poorly-controlled disease despite corticosteroid (CS) therapy. Methods: 21 severe and 30 mild asthma patients were recruited and underwent collection of blood sample. We determined whether there were any differences in inflammatory biomarkers between severe and mild asthma patients or not.Results: Levels of Interleukin-8 (IL-8) and Int...

We started on our career as parents exactly as thousands do every year; a little apprehensive , tremendously happy, unaccountably proud and more than a little at a loss. But whereas in the usual case the child manages to survive the first fumbling, weeks, thrives and learns and becomes wholly a joy, our little son did not thrive or learn, and remained for nine months a worry, as well as a joy. ...

On 28 January 1783, Joseph Black, professor of medicine and chemistry at Edinburgh Univeristy, and William Robertson, its principal, were elected honorary foreign members of the Russian Academy of Sciences. In May of that year, John Grieve, a Scottish doctor returning to Britain from service with the Russian army, wrote from Riga, as "a scholar to his old master", to inform Black of arrangement...