AIMS The excretion of low molecular weight heparin (LMWH) in breast milk was investigated in 15 lactating mothers after Caesarean section. METHODS Blood and milk samples were collected before and 3-4 h after once daily routine subcutaneous injection of 2500 IU dalteparin. Anti-Xa activity was measured by an assay utilizing prolonged clotting times in plasma or breast milk as an index of LMWH ...

Hookworms of the genus Ancylostoma secrete an anticoagulant that both inhibits the clotting of human plasma and promotes fibrin clot dissolution. This anticoagulant activity is attributable to a 36,000 dalton proteolytic enzyme. The protease can degrade fibrinogen into five smaller polypeptides that intrinsically have anticoagulating properties, covert plasminogen to a mini-plasminogen-like mol...

The composition and physical properties of raw milk from a commercial herd were studied 8 over a one year period in order to understand how best to utilise milk for processing 9 throughout the year. Protein and fat levels demonstrated seasonal trends, while minerals and 10 many physical properties displayed considerable variations, which were apparently unrelated 11 to season. However, rennet c...

Administration of vitamin K-antagonists induces the appearance of abnormal clotting factors in the blood (man, cow) or in the l iver (rat). These abnormal clotting factors (descarboxyfactors) contain glutanfc acid (G1u) residues instead of the 7-carboxyglutamic acid (Gia) residues, which occur in normal clotting factors [1]. In human and bovine plasma -90% of the abnormal proteins consists of d...