Antimicrobial, antioxidant, and anti-inflammatory activities of the essential oils of 18 plant species from Tajikistan (Central Asia) were investigated. The essential oil of Origanum tyttanthum showed a strong antibacterial activity with both minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 312.5 µg/mL for E. coli, 625 µg/mL (MIC) and 1250 µg/mL (MBC...

The gastric pathogen Helicobacter pylori has developed resistance to virtually all current antibiotics; thus, there is a pressing need to develop new anti-H. pylori therapies. The goal of this work was to evaluate the antibacterial effect of oligo-acyl-lysyl (OAK) antimicrobial peptidomimetics to determine if they might represent alternatives to conventional antibiotic treatment of H. pylori in...

Background: Red betel (Piper crocatum) is a plant that grows lot in the tropics, especially Indonesia. The use of red tropical area, leaves for medicine due to fact contain essential oils. Purpose: To examine antibacterial activity leaf extract against Staphylococcus aureus by investigate at minimum inhibitory concentration (MIC) and bactericidal (MBC) values. Methods: This study used an vitro ...

BACKGROUND AND AIMS The emergence of novel diseases caused by microbial pathogens and the undesirable side effects of certain antibiotics has been a recent dilemma in the medical arena. Consequently, it has stirred the discovery of many naturally occurring agents which could possibly provide important ramifications against various pharmacological targets and to combat various ailments. The main...

AIMS This work aimed to screen the antimicrobial activity of aqueous methanolic extracts of 13 mushroom species, collected in Bragança, against several clinical isolates obtained in Hospital Center of Trás-os-Montes and Alto Douro, Portugal. METHODS AND RESULTS Microdilution method was used to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC...

The antioxidant and antimicrobial activities of the extracts from peel, leaves, and bark of mangosteen (Garcinia mangostana L.), and some essential oils such as cinnamon and citrus were investigated. The antioxidant activities (IC50) of peel, leaves, and bark extracted, which were evaluated by DPPH method, were 5.94, 9.44, and 6.46 μg/ml, respectively. Either cinnamon or citrus essential oil sh...

The efficacy of ATP synthase inhibitor TMC207 was assessed in early and late Mycobacterium avium infections in mice. In contrast to what was earlier observed for M. tuberculosis, a bacteriostatic effect was obtained. In vitro, the minimal bactericidal concentration (MBC)/MIC ratio was very high. The MBC was more relevant for assessment of pharmacokinetic/pharmacodynamic relationships than the MIC.

Objective: The emergence of multi-drug-resistant pathogens on antimicrobials in current use has made it necessary to search for alternative treatment strategies. Plant essential oils are considered as the diseases because they non-toxic, cost-effective and accessible. This study aimed evaluate antibacterial antibiofilm effect anti-quarum sensing (QS) properties Cinnamomun verum leaf oil Pseudom...

The present investigations were aimed to evaluate the antimicrobial and antioxidant efficacies of budmunchiamine-A (BUA) of Albizia amara . The activity-guided isolation leaded to isolate the bioactive compound budmunchiamine-A from alkaloid extract of A. amara . The budmunchiamine-A showed significant broad-spectrum antimicrobial activity with zone of inhibition (ZOI), minimum inhibitory conce...

a novel chemical detergent/disinfectant formulated based on persulfate salts, germicide p , is available for disinfection of surfaces and medical devices at the room temperature. because of the resistance of hospital-resident microorganisms, the antimicrobial activity of this compound is evaluated in the present study. the tests conducted with this disinfectant included bactericidal tests again...