Abstract Background The use of sex-sorted sperm in cattle assisted reproduction is constantly increasing. However, fertility can substantially differ between unsorted (conventional) and semen batches the same sire. Sperm microRNAs (miRNA) have been suggested as promising biomarkers bull last years. In this study, we hypothesized that miRNA profile cryopreserved conventional related to after art...

1 Research Structural Engineer, Director of Aerodynamics Laboratory (HRDI-07), Federal Highway Administration, 6300 Georgetown Pike, McLean, Virginia 22101; PH (202) 493-3031; FAX (202) 493-3442; email: [email protected] 2 Hydraulic Research Engineer, GKY and Associates, Inc., 5411-E Backlick Road, Springfield, Virginia 22151; PH (703) 642-5080; FAX (703) 642-5367; email: kornel.kerenyi...

micrornas (mirnas) are a class of small non coding regulatory rnas that have key functions in multiple cell processes. deregulation of these tiny mirnas are involved in various human diseases. mir-155 is one of the multifunctional mirna that its over-expression has been found to be associated with different kinds of cancer such as leukemia, breast and colon cancers. it is thought that deregulat...

Objective(s): Autophagy-related 4B (ATG4B) plays an important role in the process of autophagy induction. However, the molecular events that govern the expression of ATG4B in this process are not well known. Materials and Methods: Human ATG4B 3'-UTR region (1377 nt) containing miR-34a/miR-34c-5p binding site was amplified by PCR. Luciferase assay was used to assess the activity of reporter gene...

Objective(s):MicroRNAs (miRNAs) are a class of short RNAs that control the biological processes including cell proliferation, apoptosis and development. Aberrant expression of miRNAs was determined in the different stages of tumor development and metastasis. To study the effect of silibinin on miRNAs expression, we evaluated quantitative expression of miR-21 and miR-155 as two oncomiRs and seve...

The Ras homolog (Rho) family of small GTPases comprise several proteins with prominent roles in regulation cell cycle transition, migration, and remodeling actin cytoskeleton. Expression these is regulated by factors among them are long non-coding RNAs (lncRNAs). impact lncRNAs on Rho signaling can be exerted through direct modulation expression or influencing miRNAs that negatively regulate GT...

† Advanced Sensing and Optical Measurement Branch, MS 493. * National Research Council Postdoctoral Fellow, Hypersonic Airbreathing Propulsion Branch; Currently at the University College, University of New South Wales, ADFA, Canberra, ACT, Australia. + Advanced Sensing and Optical Measurement Branch, MS 493; also Graduate Student in The Department of Physics at The College of William and Mary, ...