Antimycin, a specific and highly potent inhibitor of electron transfer in the cytochrome b-c1 segment of the mitochondrial respiratory chain, does not inhibit reduction of cytochrome c1 by succinate in isolated succinate-cytochrome c reductase complex under conditions where the respiratory chain complex undergoes one oxidation-reduction turnover. If a slight molar excess of cytochrome c is adde...

A real-time qPCR assay was designed to detect African-derived subspecies of western honey bees (Apis mellifera L.). The probes targeted the same region mitochondrial cytochrome b gene used in previous restriction enzyme assays. Using samples from 16 A. representing four lineages, we evaluated efficacy this identify African- (or A-lineage) and non-A-lineage bees. successfully differentiated A-li...

Chloroacetaldehyde (CAA) is a chlorination by-product in finished drinking water and a toxic metabolite of a wide variety of industrial chemicals (e.g. vinyl chloride) and chemotherapeutic agents (e.g. cyclophosphamide and ifosfamide). In this research, the cytotoxic mechanisms of CAA in freshly isolated rat hepatocytes were investigated.CAA cytotoxicity was associated with reactive oxygen spec...

Cytochrome b, coded by mitochondrial DNA, is one of the cytochromes involved in electron transport in the respiratory chain of mitochondria. Cytochrome b is a critical intermediate in a mitochondrial death pathway. To reveal whether cytochrome b of the mosquito Aedes aegypti (L.) (Diptera: Culicidae) (AeaCytB) is developmentally regulated, we used real-time quantitative polymerase chain reactio...

Abstract The East European vole Microtus mystacinus is the most widespread species in Anatolia. It also frequently seen watery habitats a large area of Eurasia. In this paper, an attempt was made to ascertain level genetic differentiation between Anatolian (Asian part Turkey) and Turkish Thracian (European populations together with additional data from other parts Asia Europe by analysing two m...

With aim of detection the spectrum of mitochondrial DNA mutations in patients with carotid atherosclerosis from Moscow Region, we used a Roche 454 high-throughput sequencing of the whole mitochondrial genome. We have found that the presence of a number of homoplasmic mitochondrial DNA mutations in genes of 16S ribosomal RNA, subunits 2, 4, and 5 NADH dehydrogenase, subunits 1 and 2 cytochrome C...

background: angiostrongylus cantonensis is a zoonotic public health concern that causes human severe eosinophilic meningitis in southeast asia and china. as a medically important intermediate host of a. cantonensis , bellamya lithophaga (gastrop-oda: viviparidae) is often confused with other morphologically similar sibling spe-cies of genus bellamya , such as b. aeruginosa and b. purificata in ...